{"created":"2023-07-27T06:29:44.487800+00:00","id":14506,"links":{},"metadata":{"_buckets":{"deposit":"8a8e592e-2eac-4e4f-b710-14d802349d45"},"_deposit":{"created_by":3,"id":"14506","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"14506"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00014506","sets":["1132:1133:1134"]},"author_link":["20086","25479","25477","25476","25478","25475","25473","25474"],"item_4_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2008-01-22","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"6","bibliographicPageStart":"1","bibliographicVolumeNumber":"47","bibliographic_titles":[{"bibliographic_title":"日本臨床細胞学会雑誌"}]}]},"item_4_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"目的: 子宮頸がん検診に従来の細胞診に HPV 検査を導入することの有用性を検討した. 方法: ベセスダシステム (2001) で意義不明の異型扁平上皮細胞を ASC と分類している. 平成 16∼18 年の 3 年間の金沢市民を対象にした行政の子宮頸がん検診において, ASC (ASC-US と ASC-H) 例にハイブリッドキャプチャー 2 (HC2) で高リスク型 HPV の検査を併用し, HPV 陽性例と軽度異形性以上の病変を推定した例にコルポスコープ下の組織検査を行い, HPV 検査導入前の 3 年間と比較検討した. 成績: 3 年間の金沢市の子宮頸がん検診受診者 3 万 3790 人中 ASC は 1565 人 (4.6%) で, そのうち 221 例 (14.1%) が HPV 陽性であった. 221 例中精検受診者は 169 例 (76.5%) で, そのなかから CIN2 以上が 27 例検出された. 浸潤がんは認めなかった. 結論: 細胞診で判定の難しい ASC 例に対し, HPV 検査を導入することによって感度が高められ, 見逃しを減らすと同時に, 不必要な生検を省くことができると考えられる. Objectives: Human papillomavirus (HPV) DNA testing was done as an adjunct to cervical cytology to evaluate its usefulness in cervical cancer screening. Study Design: Between May 2004 and March 2006, 33790 women living in Kanazawa City were screened based on Bethesda cytological classification. In cases with ASC (ASC-US and ASC-H), HPV DNA testing was done using Hybrid Capture-II. Cytology-ASC-and HPV-positive women underwent colposcopy to determine the histological diagnosis. Results: Of these 33790, 1565 (4.6%) had ASC cytology. HPV DNA was positive in 221 (14.1%) of the 1565. Of these 221, 169 (76.5%) underwent biopsy. Of these 169, 27 had disease exceeding CIN 2. Conclusions: HPV DNA testing, combined with cytology significantly improved CIN screening efficacy and avoided unnecessary biopsies.","subitem_description_type":"Abstract"}]},"item_4_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学医薬保健研究域医学系","subitem_description_type":"Other"}]},"item_4_publisher_17":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"日本臨床細胞学会雑誌 = The Japanese Society of Clinical Cytology"}]},"item_4_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://japanlinkcenter.org/JST.JSTAGE/jjscc/47.1","subitem_relation_type_select":"URI"}},{"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://www.jscc.or.jp/index.html","subitem_relation_type_select":"URI"}},{"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://ci.nii.ac.jp/naid/110006571287","subitem_relation_type_select":"URI"}}]},"item_4_rights_23":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Copyright (c) 2008 特定非営利活動法人 日本臨床細胞学会"}]},"item_4_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AN00198721","subitem_source_identifier_type":"NCID"}]},"item_4_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0387-1193","subitem_source_identifier_type":"ISSN"}]},"item_4_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"丹後, 正紘"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"金谷, 太郎"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"橋本, 茂"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"前川, 信政"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"浮田, 俊彦"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"小山, 信"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"丘村, 誠"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"井上, 正樹"}],"nameIdentifiers":[{},{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-10-03"}],"displaytype":"detail","filename":"ME-PR-INOUE-M-1.pdf","filesize":[{"value":"1.4 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"ME-PR-INOUE-M-1.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/14506/files/ME-PR-INOUE-M-1.pdf"},"version_id":"9597d237-6ee2-4f8c-b752-770cc4adbcfe"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"子宮頸がん検診における HPV 検査の導入とその有用性","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"子宮頸がん検診における HPV 検査の導入とその有用性"}]},"item_type_id":"4","owner":"3","path":["1134"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-10-03"},"publish_date":"2017-10-03","publish_status":"0","recid":"14506","relation_version_is_last":true,"title":["子宮頸がん検診における HPV 検査の導入とその有用性"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-07-28T00:46:27.046391+00:00"}