{"created":"2023-07-27T06:29:44.554137+00:00","id":14507,"links":{},"metadata":{"_buckets":{"deposit":"4eacc8ed-707a-4c4b-b891-7b7bdbc849a4"},"_deposit":{"created_by":3,"id":"14507","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"14507"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00014507","sets":["1132:1133:1134"]},"author_link":["20194","25484","25485","255","25483","25481","22034","25480","25486","25482"],"item_4_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2010-08-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"8","bibliographicPageEnd":"1363","bibliographicPageStart":"1355","bibliographicVolumeNumber":"82","bibliographic_titles":[{"bibliographic_title":"Journal of Medical Virology"}]}]},"item_4_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"To identify hepatitis C virus (HCV) transmission routes among injection drug users in Northern Vietnam, plasma samples were collected from 486 drug users in Hai Phong. Plasma viral RNA was extracted from 323 (66.5%) samples that were positive for anti-HCV antibodies. Portions of the HCV 5′- untranslated (5′UTR)-Core and NS5B genes were amplified by reverse-transcriptase polymerase chain reaction, sequenced directly, and genotyped in 194 and 195 specimens, respectively. Both regions were genotyped in 137 specimens. In the 5′UTR-Core region, genotype 6a was predominant (32.5%), followed by genotype 1a (23.7%), genotype 1b (20.6%), and genotype 6e (14.4%). In the NS5B region, genotype 1a was predominant (42.6%), followed by genotype 1b (24.1%), genotype 6a (14.4%), genotype 3b (7.2%), and genotype 6e (5.1%). Of the 137 specimens with both regions genotyped, 23 (16.8%) showed discordant genotyping results between the two regions, suggesting possible recombination and/or dual infection. Phylogenetic analysis revealed close associations between Hai Phong strains and strains from Southern China: the Yunnan province for genotype 3b; the Guangxi province for genotype 6e; the USA for genotype 1a; and Southern Vietnam for genotypes 1a and 6e. The human immunodeficiency virus (HIV) infection rate among HCV-infected injection drug users was 52.6-55.4% and did not differ significantly by HCV genotype. Most drug users infected with HIV-1 [98.8% (171/173)] were co-infected with HCV. These results suggest multiple routes of HCV transmission among injection drug users in Northern Vietnam that may also be HIV transmission routes. © 2010 Wiley-Liss, Inc.","subitem_description_type":"Abstract"}]},"item_4_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学医薬保健研究域医学系","subitem_description_type":"Other"}]},"item_4_publisher_17":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Wiley-Blackwell"}]},"item_4_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1002/jmv.21787","subitem_relation_type_select":"DOI"}}]},"item_4_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AA00702400","subitem_source_identifier_type":"NCID"}]},"item_4_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0146-6615","subitem_source_identifier_type":"ISSN"}]},"item_4_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Tanimoto, Tomoaki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Cuong, Nguyen Hung"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ishizaki, Azumi"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"Chung, Phan Thi Thu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Huyen, Hoang Thi Thanh"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Trung, Nguyen Vu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kageyama, Seiji"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Oka, Shinichi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Thuc, Pham Van"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ichimura, Hiroshi"}],"nameIdentifiers":[{},{},{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-10-03"}],"displaytype":"detail","filename":"ME-PR-ICHIMURA-H-1355.pdf","filesize":[{"value":"149.2 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"ME-PR-ICHIMURA-H-1355.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/14507/files/ME-PR-ICHIMURA-H-1355.pdf"},"version_id":"88d7ff93-17da-4ff5-82e9-a26dc7e22f79"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Multiple routes of hepatitis C virus transmission among injection drug users in Hai Phong, Northern Vietnam","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Multiple routes of hepatitis C virus transmission among injection drug users in Hai Phong, Northern Vietnam"}]},"item_type_id":"4","owner":"3","path":["1134"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-10-03"},"publish_date":"2017-10-03","publish_status":"0","recid":"14507","relation_version_is_last":true,"title":["Multiple routes of hepatitis C virus transmission among injection drug users in Hai Phong, Northern Vietnam"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-07-28T00:46:26.179416+00:00"}