@article{oai:kanazawa-u.repo.nii.ac.jp:00014530, author = {林, 浩孝 and 石橋, 範人 and 太田, 真弓 and 新井, 隆成 and 重田, 優子 and Strong, Jeffry M. and 太田, 富久 and 鈴木, 信孝}, issue = {3}, journal = {日本補完代替医療学会誌 = Japanese journal of complementary and alternative medicine}, month = {Jan}, note = {ハトムギ (Coix lacryma-jobi L. var. ma-yuen Stapf) は伝統薬として長年用いられ,抗腫瘍,抗肥満,抗糖尿などの機能をもつことが知られている.ハトムギの子実,渋皮,薄皮,外殻の全ての部分の熱水抽出物の変異原性について検討するために,細菌を用いた復帰変異試験,マウスリンフォーマ試験およびマウス小核試験を実施した.その結果,いずれの試験においても陰性の結果が得られ,被験食は生体に対し,変異原性を有する可能性はないと考えられた. Coix lacryma-jobi L. var. ma-yuen Stapf is a grass long been used in traditional medicine as a nourishing food and reported to possess pharmacological effects including anti-tumor, anti-obesity, anti-diabetic, etc. In order to evaluate the possible mutagenicity of the hot water extract of all parts (husks, pellicles, and astringent skin) of the food, we performed a reverse mutation test in bacteria, a mouse lymphoma assay and a mouse micronucleus test. The results of all tests were negative. It was concluded that the extract has no mutagenicity for living bodies.}, pages = {157--162}, title = {ハトムギ熱水抽出物の変異原性試験 : 復帰変異試験, マウスリンフォーマ試験 (MLA), マウス小核試験}, volume = {6}, year = {2009} }