@article{oai:kanazawa-u.repo.nii.ac.jp:00014549,
 author = {中本, 安成 and 寺島, 健志 and 北原, 征明 and 柿木, 嘉平太 and 荒井, 邦明 and 山下, 太郎 and 酒井, 佳夫 and 山下, 竜也 and 水腰, 英四郎 and 金子, 周一 and Takata, Yoshiko and Nakamoto, Yasunari and Nakada, Akiko and Terashima, Takeshi and Arihara, Fumitaka and Kitahara, Masaaki and Kakinoki, Kaheita and Arai, Kuniaki and Yamashita, Taro and Sakai, Yoshio and Yamashita, Tatsuya and Mizukoshi, Eishiro and Kaneko, Shuichi},
 issue = {2},
 journal = {Cancer Letters},
 month = {Aug},
 note = {The purpose of this study was to assess the properties of CD4+CD25high/low/negative T cell subsets and analyze their relation with dendritic cells (DCs) in patients with hepatocellular carcinoma (HCC). In HCC patients, the prevalence of CD45RO+ cells in CD4+CD25high T cells was increased and associated with higher frequencies of plasmacytoid DCs. Larger proportions of this T cell subset were detected in the patients with larger tumor burdens. These results suggest that increased frequencies of the CD45RO+ subset in CD4+CD25high Tregs in HCC patients may establish the immunosuppressive environment cooperatively with tolerogenic plasmacytoid DCs to promote disease progression of liver cancer. © 2011., 金沢大学先進予防医学研究センター / 金沢大学医薬保健研究域医学系},
 pages = {165--173},
 title = {Frequency of CD45RO+ subset in CD4+CD25high regulatory T cells associated with progression of hepatocellular carcinoma},
 volume = {307},
 year = {2011}
}