@article{oai:kanazawa-u.repo.nii.ac.jp:00014564,
 author = {Nomura, Akitaka and Mizukami, Yuji and Matsubara, Fujitsugu and Shimizu, Junzo and Oda, Makoto and Watanabe, Yoh and Kamimura, Ryoichi and Takashima, Tsutomu},
 issue = {6},
 journal = {Internal medicine (Tokyo, Japan)},
 month = {Jun},
 note = {Seven patients (mean age, 50.7 +/- 20.4 years; range 21-77) with plasma cell granuloma (PCG) of the lung are reported. Cough and sputum were the most common presenting symptoms, followed by fever. Elevated erythrocyte sedimentation rate and serum C-reactive protein levels were found in all patients tested. Radiologically, five cases presented as solitary, well-circumscribed masses and two as ill-defined, pneumonia-like densities. One showed focal calcification. No predilection of occurrence was observed in either lobe of the lung. Histologically, the lesions consisted of a proliferation of mature plasma cells and reticulo-endothelial cells supported by a stroma of granulation tissue, with varying degrees of myxoid change or collagenization. Angioinvasion within the lesion was observed in 4 of the 7 cases. Immunohistochemical staining revealed the IgG-predominant polyclonal nature of the plasma cells, indicating a reactive inflammatory process rather than a neoplastic one. Electron microscopy confirmed the benign nature of the plasma cells with fibroblast and myofibroblast proliferation admixed with that of other inflammatory cells., 金沢大学医薬保健研究域保健学系},
 pages = {756--765},
 title = {Seven patients with plasma cell granuloma (inflammatory pseudotumor) of the lung, including two with intrabronchial growth: an immunohistochemical and electron microscopic study.},
 volume = {31},
 year = {1992}
}