{"created":"2023-07-27T06:29:50.506216+00:00","id":14612,"links":{},"metadata":{"_buckets":{"deposit":"e897b0fe-ac93-4fc1-ae2b-f264ad1981a4"},"_deposit":{"created_by":3,"id":"14612","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"14612"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00014612","sets":["1132:1133:1134"]},"author_link":["21815","572","25886","21450","79","21455"],"item_4_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2011-04-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"487","bibliographicPageStart":"483","bibliographicVolumeNumber":"32","bibliographic_titles":[{"bibliographic_title":"Otology and Neurotology"}]}]},"item_4_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Objectives: The authors recently demonstrated that extensive bone erosion correlated with a worse prognosis of the squamous cell carcinoma (SCC) of the temporal bone. The present objective was to investigate the expressions and the roles of epithelial-mesenchymal transition (EMT) in SCC of the temporal bone. Study Design: Retrospective patient file review and immunohistochemical study of tissues of patients with SCC of the temporal bone. Patients: The authors examined the expressions of vimentin in 16 patients with SCC of the temporal bone by immunohistochemical analysis. Results: As expected, vimentin was expressed on SCC of the temporal bone. We regard the patient who has vimentin-positive cells as EMT-positive patient because gain of vimentin is a hallmark in the EMT reported in several types of cancer. EMT positive tumors significantly correlated with extensive bone erosion, and extensive bone erosion correlated with a worse prognosis of the SCC of the temporal bone. Conclusion: The study results suggest that EMT in tumor cells becomes an important indicator of poor prognosis in SCC of the temporal bone. Copyright © 2011 Otology & Neurotology, Inc. Unauthorized reproduction of this article is prohibited.","subitem_description_type":"Abstract"}]},"item_4_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学医薬保健研究域医学系","subitem_description_type":"Other"}]},"item_4_publisher_17":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Lippincott Williams & Wilkins"}]},"item_4_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1097/MAO.0b013e31820d9654","subitem_relation_type_select":"DOI"}}]},"item_4_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AA1150514X","subitem_source_identifier_type":"NCID"}]},"item_4_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1531-7129","subitem_source_identifier_type":"ISSN"}]},"item_4_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Sugimoto, Hisashi"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"Ito, Makoto"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Hatano, Miyako"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kondo, Satoru"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"Suzuki, Shioto"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"Yoshizaki, Tomokazu"}],"nameIdentifiers":[{},{},{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-10-03"}],"displaytype":"detail","filename":"ME-PR-SUGIMOTO-H-483.pdf","filesize":[{"value":"376.9 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"ME-PR-SUGIMOTO-H-483.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/14612/files/ME-PR-SUGIMOTO-H-483.pdf"},"version_id":"0dba7250-d246-4a87-a900-2e5859adec33"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Roles of epithelial-mesenchymal transition in squamous cell carcinoma of the temporal bone","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Roles of epithelial-mesenchymal transition in squamous cell carcinoma of the temporal bone"}]},"item_type_id":"4","owner":"3","path":["1134"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-10-03"},"publish_date":"2017-10-03","publish_status":"0","recid":"14612","relation_version_is_last":true,"title":["Roles of epithelial-mesenchymal transition in squamous cell carcinoma of the temporal bone"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-07-28T00:44:08.030754+00:00"}