@article{oai:kanazawa-u.repo.nii.ac.jp:00014639, author = {柴田, 和彦 and 金森, 一紀 and 吉見, 雄三 and 飯岡, 壮吾 and 藤村, 政樹 and 松田, 保}, issue = {7}, journal = {肺癌 = Japanese Journal of Lung Cancer}, month = {Dec}, note = {69歳,男性.大量心嚢水貯留のため入院.心嚢穿刺,心膜生検で癌性心膜炎と診断,原発巣は左上葉の肺癌と考えられ,T4N3M0,stageIIIBと診断された.心嚢ドレナージ,心嚢内抗癌剤注入,CDDP,VDS,MMC併用による全身化学療法3コースによって,部分寛解を得,以後病変の進行を認めなかった.初診から3年後に原発巣の増大を認め,リンパ節転移,心嚢水の再発や他臓器転移を認めないことから,salvage surgeryとして左上葉切除術を施行した.病理組織所見は低分化腺癌で形態的に3年前の心膜生検の際の腫瘍細胞と共通性が見られた.リンパ節,心膜には腫瘍の残存を認めなかった. A 69-year-old man was admitted to our hospital because of massive pericardial effusion,which was diagnosed as malignant by pericardocentesis and pericardial biopsy. He underwent surgical pericardial drainage with topical installation of cytocidal drugs. Subsequent three cycles of systemic chemotherapy consisted of cisplatin, vindesine and mitomycin C resulted in partial response. The disease did not progress until the primary nodule enlarged three years later. No recurrence of lymph node metastases and pericardial effusion or emergence of other organ metastases were seen. He underwent left upper lobectomy as salvage surgery. Histologically, the tumor was diagnosed as poorly-differentiated adenocarcinoma composed of malignant cells with morphological similarity to those found in the biopsy specimen of the pericardium three years previously. No tumor cells were found in the dissected mediastinal lymph nodes and in the re-biopsied pericardium., 金沢大学医薬保健研究域医学系}, pages = {1017--1022}, title = {3年間寛解を維持した癌性心膜炎合併非小細胞肺癌に対しsalvage surgeryを施行した1例}, volume = {37}, year = {1997} }