{"created":"2023-07-27T06:29:52.287237+00:00","id":14654,"links":{},"metadata":{"_buckets":{"deposit":"d0b7c2f0-1835-479e-8e10-6ff41d41f2b6"},"_deposit":{"created_by":3,"id":"14654","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"14654"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00014654","sets":["1132:1133:1134"]},"author_link":["26002","26000","25999","284","297","26001"],"item_4_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2010-12-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"7","bibliographicPageEnd":"911","bibliographicPageStart":"906","bibliographicVolumeNumber":"50","bibliographic_titles":[{"bibliographic_title":"Japanese Journal of Lung Cancer"}]}]},"item_4_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"背景．胸膜および肺に原発する滑膜肉腫は非常に稀である．症例．35歳，男性．右肺の異常陰影の精査目的に当院に紹介された．胸郭内原発の悪性腫瘍が疑われ，当院呼吸器外科にて胸腔鏡を行った．右胸腔内は脆弱な腫瘍で埋め尽くされていた．病理学的に，腫瘍は密に増殖する紡錘形細胞から成り，多数の核分裂像を認めた．免疫組織化学的検索を行ったが，確定診断には至らなかった．腫瘍は急速に増大し，約2ヶ月後に呼吸不全にて死亡した．剖検時，右肺は腫瘍により圧排され，虚脱していた．外科切除標本からRNAを抽出し，reverse transcription polymerase chain reaction（RT-PCR）を行い，さらにダイレクトシークエンスを行い，PCR産物がSYT-SSX2 融合遺伝子転写産物であることを確認した．胸膜以外に腫瘍を疑わせる所見を認めなかった．以上より，胸膜原発の滑膜肉腫と診断した．結論．非常に稀な腫瘍である胸膜原発の滑膜肉腫の1例を報告した．Background. Primary synovial sarcoma of the pleura and lung is extremely rare. Case. A 35-year-old man was admitted to our hospital because of an abnormal opacity in the right lung. A malignant intrathoracic tumor was suspected and a video-assisted thoracoscopic biopsy was performed. The right thoracic cavity was occupied by a fragile tumor. Histologically, the tumor showed dense proliferation of spindle cells with high rate of mitosis. Immunohistochemical examination was performed, but no definitive diagnosis was obtained. Progression of the tumor was very rapid and he died of respiratory failure 2 months after first presentation. On autopsy, the right lung was compressed and collapsed by the tumor. An SYT-SSX2 fusion gene transcript was detected by reverse transcription polymerase chain reaction (RT-PCR) and direct sequencing using RNA extracted from resected tissue specimens. There was no evidence of tumor except in the pleura. The final diagnosis was primary pleural synovial sarcoma. Conclusion. We report an extremely rare case of primary pleural synovial sarcoma. © 2010 The Japan Lung Cancer Society.","subitem_description_type":"Abstract"}]},"item_4_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学医薬保健研究域医学系","subitem_description_type":"Other"}]},"item_4_publisher_17":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"The Japan Lung Cancer Society = 日本肺癌学会"}]},"item_4_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.2482/haigan.50.906","subitem_relation_type_select":"DOI"}}]},"item_4_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://www.jstage.jst.go.jp/article/haigan/50/7/50_906/_article/-char/ja","subitem_relation_type_select":"URI"}}]},"item_4_rights_23":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Copyright (c) 2011 日本肺癌学会"}]},"item_4_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AN00203978","subitem_source_identifier_type":"NCID"}]},"item_4_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0386-9628","subitem_source_identifier_type":"ISSN"}]},"item_4_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"原, 丈介"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"西, 耕一"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"西川, 晋吾"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"常塚, 宣男"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"笠原, 寿郎"}],"nameIdentifiers":[{},{},{},{}]},{"creatorNames":[{"creatorName":"藤村, 政樹"}],"nameIdentifiers":[{},{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-10-03"}],"displaytype":"detail","filename":"ME-PR-FUJIMURA-M-906.pdf","filesize":[{"value":"1.6 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"ME-PR-FUJIMURA-M-906.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/14654/files/ME-PR-FUJIMURA-M-906.pdf"},"version_id":"e09ff51b-3ee4-40d9-8e13-5d1e6a859875"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"胸膜原発滑膜肉腫の1例","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"胸膜原発滑膜肉腫の1例"},{"subitem_title":"A case of primary pleural synovial sarcoma","subitem_title_language":"en"}]},"item_type_id":"4","owner":"3","path":["1134"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-10-03"},"publish_date":"2017-10-03","publish_status":"0","recid":"14654","relation_version_is_last":true,"title":["胸膜原発滑膜肉腫の1例"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-07-28T00:43:18.090117+00:00"}