@article{oai:kanazawa-u.repo.nii.ac.jp:00014672, author = {Watanabe, Yoh and Oda, Makoto and Shimizu, Junzo and Hayashi, Yoshinobu and Ohta, Yasuhiko and Iwa, Takashi and Tonami, Norihisa and Hisada, Kinichi}, issue = {2}, journal = {Tohoku Journal of Experimental Medicine}, month = {Feb}, note = {In a group of 27 patients with early hilar lung cancer, standard sleeve lobectomy was performed in 14 cases, standard lobectomy in 9 cases, and another 4 patients underwent parenchymal-sparing operations (2 had sleeve segmentectomy, 1 had sleeve middle lobectomy, and 1 had left second carinal resection). The changes of conventional pulmonary function tests and regional pulmonary function were compared between patients undergoing sleeve lobectomy and those undergoing parenchymal-sparing surgery. The parameters used for the conventional lung function tests were FVC, %FVC, FEV1.0, and %FEV1.0. For the evaluation of regional pulmonary function, perfusion scans using 99mTc-MAA and ventilation scans using 133Xe were performed. The decrease of FVC in the sleeve lobectomy group (n = 5) was 724 +/- 182.7 ml, whereas that in the parenchymal- sparing surgery group (n = 4) was 367.5 +/- 52.1 ml, a significant difference. Both the FEV1.0 and %FEV1.0 showed no marked changes in both groups between the preoperative and postoperative values. Perfusion and ventilation scans in the parenchymal-sparing group showed a superior result in comparison with sleeve lobectomy group. All the patients undergoing parenchymal-sparing operations survived over the long term. It was thus concluded that parenchymal-sparing surgery can be applied to carefully selected patients with tiny localized cancers., 金沢大学医薬保健研究域医学系}, pages = {135--148}, title = {Functional advantage of parenchymal-sparing surgery for early hilar lung cancer.}, volume = {163}, year = {1991} }