@article{oai:kanazawa-u.repo.nii.ac.jp:00014677,
 author = {Yamashima, Testumori and Kashihara, Kengo and kawano, Hiroichi and Kubota, Toshihiko and Hayashi, Minoru and Yamamoto, Shinjiro and 山嶋, 哲盛 and 柏原, 謙悟 and 河野, 寛一 and 久保田, 紀彦 and 林, 実 and 山本, 信二郎},
 issue = {10},
 journal = {Neurologia Medico-Chirurgica},
 month = {Jan},
 note = {Light and electron microscopic studies were conducted on myonecrosis following cerebral arterial spasm in meningitis. A 34-year-old female developed fever, headache and vomiting. Neurological examination revealed a drowsy state, nuchal stiffness and hemiparesis. Spinal puncture revealed a purulent fluid containing 1,219/mm<sup>3</sup> cells. She deteriorated steadily into semicoma 10 days after onset. Computerized tomography scan showed low density areas in bilateral basal ganglia and cerebellar hemispheres. Angiography showed vasospasm of the major cerebral arteries and vasodilatation of the left Sylvian arteries. Repeated angiography two months after onset showed a diffuse narrowing of these arteries. She died of uncal herniation 67 days after onset. Autopsy two hours after death disclosed softening in the territories of spastic arteries. Microscopically, the circle of Willis showed concentric stenosis due to an intimal proliferation. The media was remarkably atrophied and fibrotic with an infiltration of polymorphonuclear leucocytes. Electron-microscopically, the media disclosed numerous degenerating or necrotic smooth-muscle cells. The degenerating cells showed dissolution of myofilaments with resultant fine granular or filamentous material. The necrotic cells were abundant in vacuoles, lysosomes and dense bodies. The cytoplasm was eventually replaced by cellular debris and numerous collagen fibrils., 金沢大学医薬保健研究域医学系, 金沢大学附属病院脳神経外科},
 pages = {818--825},
 title = {髄膜炎による脳血管攣縮後に生じた中膜筋細胞壊死},
 volume = {25},
 year = {1985}
}