{"created":"2023-07-27T06:29:54.647565+00:00","id":14710,"links":{},"metadata":{"_buckets":{"deposit":"1f938247-0136-457a-847b-4dd4e89d898b"},"_deposit":{"created_by":3,"id":"14710","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"14710"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00014710","sets":["1132:1133:1134"]},"author_link":["20454","26182","26186","20455","26184","26185","357","26183"],"item_4_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2010-11-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"11","bibliographicPageEnd":"725","bibliographicPageStart":"717","bibliographicVolumeNumber":"55","bibliographic_titles":[{"bibliographic_title":"Journal of Human Genetics"}]}]},"item_4_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The male-specific region of Y chromosome (MSY) has accumulated a higher density of human endogenous retroviruses (HERVs) and related sequences when compared with other regions of the human genome. Here, we focused on one HERV family, HERV-K14C that seemed to integrate preferentially into the Y chromosome in humans. To identify every copies of HERV-K14C in the human genome, we applied computational screening to map precisely the locus of individual HERV-K14C copies. Interestingly, 29 of all 146 copies were located in Y chromosome, and these 29 copies were mostly dispersed in the palindromic region. Three distinct HERV-K14C-related transcripts were found and were exclusively expressed in human testis tissue. Based on our phylogenetic analysis of the solitary LTRs derived from HERV-K14C on the Y chromosome we suggested that these sequences were generated as pairs of identical sequences. Specifically, analysis of HERV-K14C-related sequences in the palindromic region demonstrated that the Y chromosomal amplicons existed in our common ancestors and the duplicated pairs arose after divergence of great apes approximately 8-10 million years ago. Taken together, our observation suggested that HERV-K14C-related sequences contributed to genomic diversification of Y chromosome during speciation of great ape lineage. © 2010 The Japan Society of Human Genetics All rights reserved.","subitem_description_type":"Abstract"}]},"item_4_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学医薬保健研究域医学系","subitem_description_type":"Other"}]},"item_4_publisher_17":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"The Japan Society of Human Genetics = 日本人類遺伝学会"}]},"item_4_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1038/jhg.2010.94","subitem_relation_type_select":"DOI"}}]},"item_4_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AA11206160","subitem_source_identifier_type":"NCID"}]},"item_4_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1434-5161","subitem_source_identifier_type":"ISSN"}]},"item_4_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Shin, Ho-Su"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Koh, Eitetsu"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"Kim, Dae-Soo"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Murayama, Miho"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sugimoto, Kazuhiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Maeda, Yuji"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"Yoshida, Atsumi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Namiki, Mikio"}],"nameIdentifiers":[{},{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-10-03"}],"displaytype":"detail","filename":"ME-PR-KOH-E-717.pdf","filesize":[{"value":"6.6 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"ME-PR-KOH-E-717.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/14710/files/ME-PR-KOH-E-717.pdf"},"version_id":"0543c89d-8f95-4888-a4dc-66ba11664457"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Human endogenous retrovirus K14C drove genomic diversification of the Y chromosome during primate evolution","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Human endogenous retrovirus K14C drove genomic diversification of the Y chromosome during primate evolution"}]},"item_type_id":"4","owner":"3","path":["1134"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-10-03"},"publish_date":"2017-10-03","publish_status":"0","recid":"14710","relation_version_is_last":true,"title":["Human endogenous retrovirus K14C drove genomic diversification of the Y chromosome during primate evolution"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-07-28T00:42:09.140626+00:00"}