@article{oai:kanazawa-u.repo.nii.ac.jp:00014727,
 author = {Okuda, Koichi and Nakajima, Kenichi and Motomura, Nobutoku and Kubota, Masahiro and Yamaki, Noriyasu and Maeda, Hisato and Matsuo, Shinro and Kinuya, Seigo},
 issue = {5},
 journal = {Annals of Nuclear Medicine},
 month = {Jul},
 note = {Objective: Segmentation with scatter and photopeak window data using attenuation correction (SSPAC) method can provide a patient-specific non-uniform attenuation coefficient map only by using photopeak and scatter images without X-ray computed tomography (CT). The purpose of this study is to evaluate the performance of attenuation correction (AC) by the SSPAC method on normal myocardial perfusion database. Methods: A total of 32 sets of exercise-rest myocardial images with Tc-99 m-sestamibi were acquired in both photopeak (140 keV ± 10%) and scatter (7% of lower side of the photopeak window) energy windows. Myocardial perfusion databases by the SSPAC method and non-AC (NC) were created from 15 female and 17 male subjects with low likelihood of cardiac disease using quantitative perfusion SPECT software. Segmental myocardial counts of a 17-segment model from these databases were compared on the basis of paired t test. Results: AC average myocardial perfusion count was significantly higher than that in NC in the septal and inferior regions (P < 0.02). On the contrary, AC average count was significantly lower in the anterolateral and apical regions (P < 0.01). Coefficient variation of the AC count in the mid, apical and apex regions was lower than that of NC. Conclusions: The SSPAC method can improve average myocardial perfusion uptake in the septal and inferior regions and provide uniform distribution of myocardial perfusion. The SSPAC method could be a practical method of attenuation correction without X-ray CT. © 2009 The Japanese Society of Nuclear Medicine., 金沢大学医薬保健研究域},
 pages = {501--506},
 title = {Attenuation correction of myocardial SPECT by scatter-photopeak window method in normal subjects},
 volume = {23},
 year = {2009}
}