{"created":"2023-07-27T06:29:56.223366+00:00","id":14747,"links":{},"metadata":{"_buckets":{"deposit":"c2aaa658-cc46-47aa-9c6b-56cccfc75457"},"_deposit":{"created_by":3,"id":"14747","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"14747"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00014747","sets":["1132:1133:1134"]},"author_link":["21219","297","26330","71","26329","1191"],"item_4_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2010-10-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"306","bibliographicPageStart":"301","bibliographicVolumeNumber":"17","bibliographic_titles":[{"bibliographic_title":"Journal of Bronchology"}]}]},"item_4_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Background and Objective: The purpose of this study was to evaluate the relationship between the wall structure assessed by using endobronchial ultrasonography (EBUS) and bronchial hyperresponsiveness in patients with asthma. Methods: Twenty-four patients with stable asthma and 11 individuals without asthma were studied. EBUS was performed with a radial 20-MHz ultrasonic probe inserted into the intermediate bronchus undergoing flexible bronchoscopy to assess the airway wall structure. The percentage of airway wall thickness {WT%; defined as [(ideal outer diameter-ideal luminal diameter)/ideal outer diameter] × 100} was determined by EBUS. We measured bronchial hyperresponsiveness to methacholine [the provocative concentration of methacholine causing a decrease of 20% or more in forced expiratory volume in 1 s (PC20)]. Results: Percentage wall thickness measured by EBUS was significantly greater in patients with asthma than that in subjects without asthma (P < 0.01). The evaluation of the laminar structure using EBUS indicated that the thickness of the second layer in patients with asthma was greater than that in subjects without asthma (P < 0.05). PC20 was negatively correlated with the thickness of the second layer (r=0.52, P < 0.01) but was not significantly correlated with other layers in patients with asthma. Conclusions: The evaluation of the bronchial mural structure using EBUS might be advantageous for assessing the relationship between airway wall remodeling and bronchial hyperresponsiveness. © 2010 Lippincott Williams & Wilkins.","subitem_description_type":"Abstract"}]},"item_4_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学医薬保健研究域医学系","subitem_description_type":"Other"}]},"item_4_publisher_17":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Lippincott Williams & Wilkins"}]},"item_4_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1097/LBR.0b013e3181f9f09b","subitem_relation_type_select":"DOI"}}]},"item_4_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AA11016143","subitem_source_identifier_type":"NCID"}]},"item_4_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1070-8030","subitem_source_identifier_type":"ISSN"}]},"item_4_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Kita, Toshiyuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Fujimura, Masaki"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"Sone, Takashi"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Inuzuka, Kanako"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Myou, Shigeharu"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"Nakao, Shinji"}],"nameIdentifiers":[{},{},{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-10-03"}],"displaytype":"detail","filename":"ME-PR-FUJIMURA-M-301.pdf","filesize":[{"value":"205.2 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"ME-PR-FUJIMURA-M-301.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/14747/files/ME-PR-FUJIMURA-M-301.pdf"},"version_id":"8f7db3f4-6d29-4951-a6d1-fe378d99f9a4"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Airway wall structure assessed by endobronchial ultrasonography and bronchial hyperresponsiveness in patients with asthma","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Airway wall structure assessed by endobronchial ultrasonography and bronchial hyperresponsiveness in patients with asthma"}]},"item_type_id":"4","owner":"3","path":["1134"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-10-03"},"publish_date":"2017-10-03","publish_status":"0","recid":"14747","relation_version_is_last":true,"title":["Airway wall structure assessed by endobronchial ultrasonography and bronchial hyperresponsiveness in patients with asthma"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-07-28T00:41:34.669761+00:00"}