{"created":"2023-07-27T06:29:56.516356+00:00","id":14754,"links":{},"metadata":{"_buckets":{"deposit":"46815260-0699-400d-afe4-3d8f31d3838e"},"_deposit":{"created_by":3,"id":"14754","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"14754"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00014754","sets":["1132:1133:1134"]},"author_link":["519","10713","186","26351"],"item_4_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2003-12-30","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"7","bibliographicPageEnd":"966","bibliographicPageStart":"961","bibliographicVolumeNumber":"43","bibliographic_titles":[{"bibliographic_title":"Japanese Journal of Lung Cancer = 肺癌"}]}]},"item_4_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Purpose. In the has 4 years, we performed chemotherapy using paclitaxel (TXL) for 20 cases of recurrent non-small cell lung cancer and two cases of residual lung cancer patients. In this report, we present two cases showing complete remission. Case 1. The patient was a 69-year-old man who underwent an operation for stage IA adenocarcinoma. Thirty-eight months after the operation, this patient showed intrathoracic recurrence. No response was available after three couses of treatment using CDDP+VDS. This case was diagnosed as metachronous double primary lung cancer after the re-operation. Multiple recurrent tumors appeared in his left lung. Complete response was obtained after four courses of CBDCA+TXL. The patient is alive with no recurrence after seven courses of weekly TXL. Case 2. A 50-year old women underwent a non-curative operation for the tumor in the right S10 with intrathoracic dissemination. The pathological diagnosis was pT4NOM1, stage IV. The weekly TXL therapy was started because the residual tumors revelaed no response to the three courses of CBDCA+TXL. Complete response was obtained 20 months after the weekly TXL, therapy was started. The patient is alive with no sign of recurrence after 25 courses of weekly TXL therapy. Conclusion. Chemotherapy using TXL may be a promising regimen for the treatment of recurrent or residual non-small cell lung cancer. 目的.最近4年間に,非小細胞肺癌術後再発20例および術後癌遺残2例の計22例に対してパクリタキセルを用いた化学療法を施行した.このうちComplete Response (CR)が得られた2例を呈示する.症例1.69歳,男性.右腺癌(IA期)に対し手術を施行した.胸腔内再発を来し,シスプラチン+ビンデシンを3コース施行するも不変(NC)であった.再手術にて,多発癌と診断された.その後左肺に多発転移巣を認めたため,カルボプラチン+パクリタキセルを4コース施行し,転移巣はほぼ消失した.パクリタキセル隔週投与を計7コース施行し,現在再発の徴候は認めていない.症例2.50歳,女性.胸膜播種を伴う右S10の腫瘍に対して,手術(非完全切除)を施行した.中分化型腺癌(pT4NOM1,IV期)と診断された.カルボプラチン+パクリタキセルを3コース施行したが術後遺残した肺転移巣はNCであったため,パクリタキセル隔週投与を開始した.20ヵ月後CRが得られ,計25コース終了時点で一旦化学療法を中止した.現在無再発生存中である.結論.非小細胞肺癌に対するパクリタキセルを用いた化学療法は,術後再発例や癌遺残例に対しても治療の一選択肢となり得ると考えられた.","subitem_description_type":"Abstract"}]},"item_4_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"医薬保健研究域医学系","subitem_description_type":"Other"}]},"item_4_publisher_17":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Japanese Lung Cancer Society = 日本肺癌学会"}]},"item_4_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://www.haigan.gr.jp/","subitem_relation_type_select":"URI"}},{"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://ci.nii.ac.jp/naid/110003138490","subitem_relation_type_select":"URI"}}]},"item_4_rights_23":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Copyright (c) 2003 日本肺癌学会 : 本文データは学協会の許諾に基づきCiNiiから複製したものである relation: isVersionOf: http://ci.nii.ac.jp/naid/110003138490"}]},"item_4_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AN00203978","subitem_source_identifier_type":"NCID"}]},"item_4_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0386-9628","subitem_source_identifier_type":"ISSN"}]},"item_4_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"小田, 誠"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"谷内, 毅"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"田村, 昌也"}],"nameIdentifiers":[{},{},{},{}]},{"creatorNames":[{"creatorName":"渡邊, 剛"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-10-03"}],"displaytype":"detail","filename":"ME-PR-ODA-M-961.pdf","filesize":[{"value":"2.3 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"ME-PR-ODA-M-961.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/14754/files/ME-PR-ODA-M-961.pdf"},"version_id":"31f4d98a-e759-4174-bf4b-e8b3890726d2"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"肺癌術後癌遺残,再発例に対するパクリタキセルの著効例(第18回日本肺癌学会肺癌ワークショップ)","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"肺癌術後癌遺残,再発例に対するパクリタキセルの著効例(第18回日本肺癌学会肺癌ワークショップ)"},{"subitem_title":"Chemotherapy of Two Cases of Recurrent or Residual Non-small Cell Lung Cancer Responding Completely to Paclitaxel","subitem_title_language":"en"}]},"item_type_id":"4","owner":"3","path":["1134"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-10-03"},"publish_date":"2017-10-03","publish_status":"0","recid":"14754","relation_version_is_last":true,"title":["肺癌術後癌遺残,再発例に対するパクリタキセルの著効例(第18回日本肺癌学会肺癌ワークショップ)"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-07-28T00:41:25.139146+00:00"}