@article{oai:kanazawa-u.repo.nii.ac.jp:00014762, author = {Ohba, Masashi and Izuta, Rie and Shimizu, Emi}, issue = {1}, journal = {Chemical and Pharmaceutical Bulletin}, month = {Jan}, note = {A full account of the total synthesis of two monoterpene alkaloids, (-)-plectrodorine [(-)-1] and (+)-oxerine [(+)-3], is presented. The key steps involved are the formation of the oxazole alcohol 10 from the γ-butyrolactone 9 and the intramolecular Diels-Alder reaction of the oxazole-olefins 13a, b. Since the sign of specific rotation for the synthetic (+)-3 was different from that reported for natural oxerine, the absolute configuration of this alkaloid is not yet fully understood. © 2006 Pharmaceutical Society of Japan.}, pages = {63--67}, title = {Use of the oxazole-olefin Diels-Alder reaction in the total synthesis of the monoterpene alkaloids (-)-plectrodorine and (+)-oxerine}, volume = {54}, year = {2006} }