WEKO3
インデックスリンク
アイテム
Latams. X. The Alkaline Ferricyanide Oxidation of 3-Substituted 1-(3,4-Dimethoxyphenethyl) pyridinium Salts : Effects of Functional Substituents
http://hdl.handle.net/2297/7620
http://hdl.handle.net/2297/76209d067395-f65c-4994-bf3f-c5f2ef2b59e9
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
PH-PR-OHBA-M-2887.pdf (1.6 MB)
|
|
| Item type | 学術雑誌論文 / Journal Article(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2017-10-03 | |||||
| タイトル | ||||||
| タイトル | Latams. X. The Alkaline Ferricyanide Oxidation of 3-Substituted 1-(3,4-Dimethoxyphenethyl) pyridinium Salts : Effects of Functional Substituents | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | journal article | |||||
| 著者 |
Fujii, Tozo
× Fujii, Tozo× Ohba, Masashi× Yoshifuji, Shigeyuki× Kirihara, Makoto |
|||||
| 書誌情報 |
Chemical & pharmaceutical bulletin 巻 25, 号 11, p. 2887-2894, 発行日 1977-11-25 |
|||||
| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 0009-2363 | |||||
| NCID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00602100 | |||||
| DOI | ||||||
| 関連タイプ | isIdenticalTo | |||||
| 識別子タイプ | DOI | |||||
| 関連識別子 | 10.1248/cpb.25.2887 | |||||
| 出版者 | ||||||
| 出版者 | 日本薬学会 | |||||
| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | In the alkaline ferricyanide oxidation at 32°of 3-substituted 1-(3,4-dimethoxyphenethyl) pyridinium bromides (type 3), the hydroxymethyl, N, N-dimethylaminomethyl, carbamoyl, and 1,1-ethylenedithioethyl groups at the 3-position have been found to orient the oxidation to both the 2-(type 4) and the 6-position (type 5) in ratios of 70 : 30,26 : 74,50 : 50,and 4 : 96. The carboxyl or 1,1-ethylenedioxyethyl group at the 3-position has oriented the oxidation to the 6-position exclusively, and possible factors in determining the regioselectivity in the ferricyanide oxidation of the 1,3-disubstituted pyridinium salts are discussed. For preparation of additional pyridone derivatives, 1-(3,4-dimethoxyphenethyl)-5-carboxy-2(1H)-pyridone (5d) was esterified with methanolic hydrogen chloride to the methyl ester (5h), and 1-(3,4-dimethoxyphenethyl)-5-(1,1-ethylenedioxyethyl)-2 (1H)-pyridone (5e) was converted into the methyl ketone (5i) by acid hydrolysis. The structures of the pyridones (4a, b, c, f, 5a-i) thus prepared have assigned on the basis of their ultraviolet, infrared, and nuclear magnetic resonance spectra. | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
