{"created":"2023-07-27T06:30:00.184124+00:00","id":14840,"links":{},"metadata":{"_buckets":{"deposit":"25504d89-72df-4df2-9c55-8976078cea39"},"_deposit":{"created_by":3,"id":"14840","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"14840"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00014840","sets":["1132:1133:1135"]},"author_link":["26369","26598","26599"],"item_4_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1995-01-15","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"52","bibliographicPageStart":"49","bibliographicVolumeNumber":"43","bibliographic_titles":[{"bibliographic_title":"Chemical & pharmaceutical bulletin"}]}]},"item_4_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"A detailed account is given of the first chiral synthesis of the Ophiorrhiza alkaloid ophiorrhizine [(-)-1]. The synthesis was started by coupling the lactim ether (+)-4, readily available from cincholoipon ethyl ester [(+)-3], with 6-benzyloxy-3-chloroacetylindole (6) to form the lactam ketone (+)-8 and proceeded through the intermediates (+)-9, (+)-10, 11, (-)-12, (-)-13, 14, (-)-15, and (-)-16. The identity of synthetic (-)-1·H2O with natural ophiorrhizine unequivocally established the absolute stereochemistry of this alkaloid.","subitem_description_type":"Abstract"}]},"item_4_publisher_17":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"日本薬学会"}]},"item_4_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1248/cpb.43.49","subitem_relation_type_select":"DOI"}}]},"item_4_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AA00602100","subitem_source_identifier_type":"NCID"}]},"item_4_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0009-2363","subitem_source_identifier_type":"ISSN"}]},"item_4_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Fujii, Tozo"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ohba, Masashi"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"Seto, Shigeki"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-10-03"}],"displaytype":"detail","filename":"PH-PR-OHBA-M-49.pdf","filesize":[{"value":"945.8 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"PH-PR-OHBA-M-49.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/14840/files/PH-PR-OHBA-M-49.pdf"},"version_id":"bb2e87ff-1d24-49e5-bfb0-fd4f5ceef3b4"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Bischler-Napieralski cyclization","subitem_subject_scheme":"Other"},{"subitem_subject":"Cincholoipon","subitem_subject_scheme":"Other"},{"subitem_subject":"Lactim ether N-alkylation","subitem_subject_scheme":"Other"},{"subitem_subject":"Ophiorrhiza alkaloid synthesis","subitem_subject_scheme":"Other"},{"subitem_subject":"Ophiorrhizine configuration","subitem_subject_scheme":"Other"},{"subitem_subject":"Oxazolium hydrogenolysis","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Quinolizidines. XXXIII. A chiral synthesis of (-)-ophiorrhizine, a pentacyclic quaternary indole alkaloid from ophiorrhiza major RIDL","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Quinolizidines. XXXIII. A chiral synthesis of (-)-ophiorrhizine, a pentacyclic quaternary indole alkaloid from ophiorrhiza major RIDL"}]},"item_type_id":"4","owner":"3","path":["1135"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-10-03"},"publish_date":"2017-10-03","publish_status":"0","recid":"14840","relation_version_is_last":true,"title":["Quinolizidines. XXXIII. A chiral synthesis of (-)-ophiorrhizine, a pentacyclic quaternary indole alkaloid from ophiorrhiza major RIDL"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-07-27T12:25:57.544953+00:00"}