{"created":"2023-07-27T06:30:01.627531+00:00","id":14874,"links":{},"metadata":{"_buckets":{"deposit":"85cfb3ad-3c1e-48d7-bb00-3da8a1e7fb8d"},"_deposit":{"created_by":3,"id":"14874","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"14874"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00014874","sets":["1132:1133:1135"]},"author_link":["26431","26689","26429","26687","26688"],"item_4_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2007-09-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"9","bibliographicPageEnd":"1656","bibliographicPageStart":"1653","bibliographicVolumeNumber":"30","bibliographic_titles":[{"bibliographic_title":"Biological and Pharmaceutical Bulletin"}]}]},"item_4_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"A method for the determination of digoxin in human serum using a liquid chromatography/electrospray ionization-tandem mass spectrometry (LC/ESI-MS/MS) technique is reported. Digoxin and the internal standard, [21,21,22- 2H3]digoxin, were extracted from 250 μl of human serum using a solid phase extraction cartridge (Oasis HLB) and analyzed by LC/ESI-MS/MS in the selected reaction monitoring mode. The intra- and interassay reproducibility and accuracy were satisfactory within the quantification range of 0.20-3.20 ng/ml. The concentrations of digoxin in the serum samples obtained from digitalized patients (n=19) were in the range of 0.25-2.84 ng/ml, which were compared to those obtained by radioimmunoassay. © 2007 Pharmaceutical Society of Japan.","subitem_description_type":"Abstract"}]},"item_4_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学大学院自然科学研究科分子作用学","subitem_description_type":"Other"},{"subitem_description":"金沢大学薬学部","subitem_description_type":"Other"}]},"item_4_publisher_17":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"日本薬学会"}]},"item_4_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1248/bpb.30.1653","subitem_relation_type_select":"DOI"}}]},"item_4_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://www.jstage.jst.go.jp/article/bpb/30/9/30_1653/_article","subitem_relation_type_select":"URI"}}]},"item_4_rights_23":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"(c) 2007 The Pharmaceutical Society of Japan"}]},"item_4_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AA10885497","subitem_source_identifier_type":"NCID"}]},"item_4_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0918-6158","subitem_source_identifier_type":"ISSN"}]},"item_4_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Mitamura, Kuniko"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"Horikawa, Aki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yamane, Yuko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Ikeda, Yukari"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Shimada, Kazutake"}],"nameIdentifiers":[{},{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-10-03"}],"displaytype":"detail","filename":"PH-PR-SHIMADA-K-1653.pdf","filesize":[{"value":"113.4 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"PH-PR-SHIMADA-K-1653.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/14874/files/PH-PR-SHIMADA-K-1653.pdf"},"version_id":"90349db0-ee6f-44bd-8498-12503c9fa966"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Determination of digoxin in human serum using stable isotope dilution liquid chromatography/electrospray ionization-tandem mass spectrometry","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Determination of digoxin in human serum using stable isotope dilution liquid chromatography/electrospray ionization-tandem mass spectrometry"}]},"item_type_id":"4","owner":"3","path":["1135"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-10-03"},"publish_date":"2017-10-03","publish_status":"0","recid":"14874","relation_version_is_last":true,"title":["Determination of digoxin in human serum using stable isotope dilution liquid chromatography/electrospray ionization-tandem mass spectrometry"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-07-28T00:40:41.879366+00:00"}