@article{oai:kanazawa-u.repo.nii.ac.jp:00014893, author = {Tokue, Takanori and Miura, Shunsuke and Kato, Hikaru and Hirota, Hiroshi and Ohta, Tomihisa and Tsukamoto, Sachiko}, issue = {1}, journal = {Heterocycles}, month = {Dec}, note = {The MeOH extract of a marine sponge of the genus Spongia showed neurotrophic activity in pheochromocytoma (PC-12) cells. Purification of the extract afforded a new sesterterpene, deacetoxyscalarin (1), along with five known sesterterpenes (2-6). Among them, 2-6 induced neurite outgrowth in PC-12 cells at the concentration of 50 μg/mL but 1 was inactive. © 2006 The Japan Institute of Heterocyclic Chemistry., 金沢大学大学院自然科学研究科生理活性物質科学, 金沢大学薬学部}, pages = {521--526}, title = {Neurotrophic sesterterpenes isolated from a marine sponge, Spongia sp.}, volume = {69}, year = {2006} }