@article{oai:kanazawa-u.repo.nii.ac.jp:00014911, author = {Fujii, Tozo and Ohba, Masashi and Kogen, Hiroshi and Ueda, Yuko}, issue = {11}, journal = {Chemical & pharmaceutical bulletin}, month = {Nov}, note = {The thermal decarboxylation of some unsaturated acids (1,5,6,8,and 9) incorporated into six-membered lactams was examined. Although 8 and 9 did not undergo decarboxylation when heated neat at 175-180℃ and 240-245℃, respectively, for 2 h, 1,5,and 6 were decarboxylated in 1,1,2,2-tetrachloroethane at 135℃. The relative ease of the reaction was in the order of 1≥6≫5. In the case of 1,the rate-decreasing effects observed on dilution and on the addition of trichloroacetic acid suggest the reaction to be a dimeric intermolecular process.}, pages = {3392--3397}, title = {Lactams. XX. Decarboxylation of Unsaturated Acids incorporated into Six-Membered Lactam Systems}, volume = {29}, year = {1981} }