@article{oai:kanazawa-u.repo.nii.ac.jp:00014941, author = {Yamada, Koji and Yamada, Fumio and Somei, Masanori}, issue = {2}, journal = {Heterocycles}, month = {Mar}, note = {1-Hydroxytryptamine derivatives undergo nucleophilic substitution reaction on the indole nitrogen (Na) as a general reaction by the treatment with acid, providing a novel synthetic method for 1-aryltryptamines. Depending on the structures of nucleophiles, 5- and 7-substituted tryptamines can also be produced in addition to the 1-aryltryptamines., An easy approach to 7-substituted 4,5-dihydro-7H-pyrano[3,4-c]-isoxazole derivatives (3a-b and 6a-d) is described by the reaction of 2-aryl substituted 1-nitro-3-oxa-6-heptynes (2, 5a and 5b) with n-BuLi, followed by treatment with acetic anhydride., 金沢大学大学院自然科学研究科生理活性物質科学}, pages = {685--690}, title = {Preparation of 7-substituted 4,5-dihydro-7H-pyrano[3,4-c]-isoxazole derivatives}, volume = {59}, year = {2002} }