{"created":"2023-07-27T06:30:08.657828+00:00","id":15037,"links":{},"metadata":{"_buckets":{"deposit":"9e1db93c-48bc-4dd7-99b2-cc6404d164e7"},"_deposit":{"created_by":3,"id":"15037","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"15037"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00015037","sets":["1132:1133:1135"]},"author_link":["27024","112","27023","26985"],"item_4_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1992-06-20","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"178","bibliographicPageStart":"174","bibliographicVolumeNumber":"46","bibliographic_titles":[{"bibliographic_title":"生薬学雑誌 = The Japanese journal of pharmacognosy"}]}]},"item_4_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"大黄の化学的な品質評価については,吸光度法による総結合型アソトラキノン類の定量,HPLC法あるいは近赤外分光分析計を用いたsennoside A, B(SA,SB)の定量,HPLCグラジエント法による多成分同時定量法など多くの報告がある.しかし,それらの定量法は,操作が煩雑であったり,また高価な機器を必要としている.われわれは色彩計を用いて,生薬の色彩と品質の関係について検討している. 今回,市場品大黄18検体の粉末や水抽出液の色を測定し,市販のデータ解析ソフトを利用して,原植物および含有成分anthrones (AR), anthraquinones (AQ), catechin (CA), gallic acid (GA),加水分解して得られるgallic acidの総量(Hy-GA)などの定量値との相関性を調査した.その結果,水抽出液を塩化第二鉄試液で発色させたときの色彩値とARおよびHy-GAとの間に高い相関性が得られ,色彩計を用いて大黄の成分化学的な品質評価が容易に行いうることを明らかにしたので報告する. Quality evaluation of commercial Rhubarbs was made by using a colorimeter. No correlation was found between the botanical origin, the colors of fine powder and water extracts of the drug, and the amounts of chemical constituents such as anthraquinones (AQ), anthrones (AR), sennoside A, B (SA, SB), catechin (CA), gallic acid (GA) and total gallic acid obtained by hydrolysis (Hy-GA). On the other hand, the colors of water extracts, particularly the color developed on the addition of ferric chloride, showed a high correlation with the amounts of some chemical constituents: the correlation coefficient between AR and b^* value of the color was 0.895, and that between Hy-GA and color tone was -0.832. The above results indicate that the colorimetric method may provide a rapid and easy procedure highly useful for the estimation of the amounts of some chemical constituents in Rhubarb.","subitem_description_type":"Abstract"}]},"item_4_publisher_17":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"日本生薬学会 = The Japanese Society of Pharmacognosy"}]},"item_4_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://www.jsphcg.gr.jp/","subitem_relation_type_select":"URI"}},{"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://www.jsphcg.gr.jp/publication.html/","subitem_relation_type_select":"URI"}},{"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://ci.nii.ac.jp/naid/110008908353/","subitem_relation_type_select":"URI"}}]},"item_4_rights_23":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Copyright © 日本生薬学会 The Japanese Society of Pharmacognosy"}]},"item_4_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AN00116895","subitem_source_identifier_type":"NCID"}]},"item_4_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0037-4377","subitem_source_identifier_type":"ISSN"}]},"item_4_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"近藤, 誠三"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"御影, 雅幸"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"高野, 昭人"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"津田, 喜典"}],"nameIdentifiers":[{},{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-10-04"}],"displaytype":"detail","filename":"PH-PR-MIKAGE-M-174.pdf","filesize":[{"value":"2.3 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"PH-PR-MIKAGE-M-174.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/15037/files/PH-PR-MIKAGE-M-174.pdf"},"version_id":"3f4c0a01-52a1-43f2-bbe1-f2ebba137db0"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"色彩計による生薬の品質評価(第2報): 大黄の色彩と含有成分量","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"色彩計による生薬の品質評価(第2報): 大黄の色彩と含有成分量"},{"subitem_title":"Studies on the Evaluation of Crude Drugs by Means of Colorimeter (2) : Correlation between the Color and Chemical Constituents of Rhubarb","subitem_title_language":"en"}]},"item_type_id":"4","owner":"3","path":["1135"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-10-04"},"publish_date":"2017-10-04","publish_status":"0","recid":"15037","relation_version_is_last":true,"title":["色彩計による生薬の品質評価(第2報): 大黄の色彩と含有成分量"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-07-28T00:39:28.336332+00:00"}