@article{oai:kanazawa-u.repo.nii.ac.jp:00015079, author = {Sakurai, Ikuo and Miyajima, Hisae and Akiyama, Katsuyoshi and Shimizu, Sakae and Yamamoto, Yuzuru}, issue = {6}, journal = {Chemical & pharmaceutical bulletin}, month = {Jun}, note = {Substrate specificity in the novel biotransformation from 2-pyrone derivatives to substituted benzoic acids by Macrophoma commelinae (IFO 9570) was investigated by means of feeding experiments with various compounds. Among them, 2-pyrone derivatives substituted by an electron-donating group at C-4,by an electron-withdrawing group at C-5 and by an alkyl group at C-6 were converted to the corresponding benzoic acid derivatives in fairly good yields. The C_3-unit precursors and intermediates were examined in stationary or shaking culture. Based on the experimental results obtained, a mechanism for this unique reaction is proposed.}, pages = {2003--2011}, title = {Studies on Metabolites of Macrophoma commelinae. IV. : Substrate Specificity in the Biotransformation of 2-Pyrones to Substituted Benzoic Acids}, volume = {36}, year = {1988} }