@article{oai:kanazawa-u.repo.nii.ac.jp:00015083, author = {Shimizu, Sakae and Yamamoto, Yuzuru and Koshimura, Saburo}, issue = {5}, journal = {Chemical & pharmaceutical bulletin}, month = {May}, note = {An attempt was made to obtain more potent antitumor compounds by chemically modifying asterriquinones. Amino-and aziridinyl-asterriquinone were newly synthesized, but showed no activity. However, dimethylallylation of asterriquinone Cl, which had no effect in vivo, yielded an active compound, with a change in pKa value from 5.0 to 7.2. This suggests that other active compounds may be obtained by the chemical modification of asterriquinones with various other functional groups.}, pages = {1896--1899}, title = {Antitumor Activity of Asterriquinones from Aspergillus Fungi. IV. An Attempt to modify the Structure of Asterriquinones to increase the Activity}, volume = {30}, year = {1982} }