{"created":"2023-07-27T06:30:11.463116+00:00","id":15104,"links":{},"metadata":{"_buckets":{"deposit":"02f4a7b5-2436-4ac7-9559-265fbcd75133"},"_deposit":{"created_by":3,"id":"15104","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"15104"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00015104","sets":["4281:4291:4312"]},"author_link":["27220","27215","27221","27214","76136","2408","83077","27217","27216","27219","1475","83092","531","27218","562"],"item_4_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2014-01-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageStart":"13","bibliographicVolumeNumber":"15","bibliographic_titles":[{"bibliographic_title":"BMC pharmacology & toxicology"}]}]},"item_4_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"吉田, 直子"}],"nameIdentifiers":[{"nameIdentifier":"562","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"20565428","nameIdentifierScheme":"金沢大学研究者情報","nameIdentifierURI":"http://ridb.kanazawa-u.ac.jp/public/detail.php?kaken=20565428"},{"nameIdentifier":"20565428","nameIdentifierScheme":"研究者番号","nameIdentifierURI":"https://nrid.nii.ac.jp/nrid/1000020565428"}]},{"creatorNames":[{"creatorName":"赤沢, 学"}],"nameIdentifiers":[{"nameIdentifier":"83092","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"坪井, 宏仁"}],"nameIdentifiers":[{"nameIdentifier":"2408","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"20319338","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=20319338"}]},{"creatorNames":[{"creatorName":"谷本, 剛"}],"nameIdentifiers":[{"nameIdentifier":"83077","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"80142123","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=80142123"}]},{"creatorNames":[{"creatorName":"木村, 和子"}],"nameIdentifiers":[{"nameIdentifier":"531","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"80324094","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=80324094"},{"nameIdentifier":"80324094","nameIdentifierScheme":"研究者番号","nameIdentifierURI":"https://nrid.nii.ac.jp/nrid/1000080324094"}]}]},"item_4_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Access to good-quality medicines in many countries is largely hindered by the rampant circulation of spurious/falsely labeled/falsified/counterfeit (SFFC) and substandard medicines. In 2006, the Ministry of Health of Cambodia, in collaboration with Kanazawa University, Japan, initiated a project to combat SFFC medicines. To assess the quality of medicines and prevalence of SFFC medicines among selected products, a cross-sectional survey was carried out in Cambodia. Cefixime, omeprazole, co-trimoxazole, clarithromycin, and sildenafil were selected as candidate medicines. These medicines were purchased from private community drug outlets in the capital, Phnom Penh, and Svay Rieng and Kandal provinces through a stratified random sampling scheme in July 2010. In total, 325 medicine samples were collected from 111 drug outlets. Non-licensed outlets were more commonly encountered in rural than in urban areas (p < 0.01). Of all the samples, 93.5% were registered and 80% were foreign products. Samples without registration numbers were found more frequently among foreign-manufactured products than in domestic ones (p < 0.01). According to pharmacopeial analytical results, 14.5%, 4.6%, and 24.6% of the samples were unacceptable in quantity, content uniformity, and dissolution test, respectively. All the ultimately unacceptable samples in the content uniformity tests were of foreign origin. Following authenticity investigations conducted with the respective manufacturers and medicine regulatory authorities, an unregistered product of cefixime collected from a pharmacy was confirmed as an SFFC medicine. However, the sample was acceptable in quantity, content uniformity, and dissolution test. The results of this survey indicate that medicine counterfeiting is not limited to essential medicines in Cambodia: newer-generation medicines are also targeted. Concerted efforts by both domestic and foreign manufacturers, wholesalers, retailers, and regulatory authorities should help improve the quality of medicines.","subitem_description_type":"Abstract"}]},"item_4_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00015091","subitem_identifier_reg_type":"JaLC"}]},"item_4_publisher_17":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"BioMed Central"}]},"item_4_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1186/2050-6511-15-13","subitem_relation_type_select":"DOI"}}]},"item_4_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"2050-6511","subitem_source_identifier_type":"ISSN"}]},"item_4_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Yoshida, Naoko"}],"nameIdentifiers":[{"nameIdentifier":"562","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"20565428","nameIdentifierScheme":"金沢大学研究者情報","nameIdentifierURI":"http://ridb.kanazawa-u.ac.jp/public/detail.php?kaken=20565428"},{"nameIdentifier":"20565428","nameIdentifierScheme":"研究者番号","nameIdentifierURI":"https://nrid.nii.ac.jp/nrid/1000020565428"}]},{"creatorNames":[{"creatorName":"Khan, Mohiuddin Hussain"}],"nameIdentifiers":[{"nameIdentifier":"27214","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tabata, Hitomi"}],"nameIdentifiers":[{"nameIdentifier":"27215","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Dararath, Eav"}],"nameIdentifiers":[{"nameIdentifier":"27216","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Sovannarith, Tey"}],"nameIdentifiers":[{"nameIdentifier":"27217","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Kiet, Heng Bun"}],"nameIdentifiers":[{"nameIdentifier":"27218","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Nivanna, Nam"}],"nameIdentifiers":[{"nameIdentifier":"27219","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Akazawa, Manabu"}],"nameIdentifiers":[{"nameIdentifier":"27220","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Tsuboi, Hirohito"}],"nameIdentifiers":[{"nameIdentifier":"27221","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"20319338","nameIdentifierScheme":"金沢大学研究者情報","nameIdentifierURI":"http://ridb.kanazawa-u.ac.jp/public/detail.php?kaken=20319338"},{"nameIdentifier":"20319338","nameIdentifierScheme":"研究者番号","nameIdentifierURI":"https://nrid.nii.ac.jp/nrid/1000020319338"}]},{"creatorNames":[{"creatorName":"Tanimoto, Tsuyoshi"}],"nameIdentifiers":[{"nameIdentifier":"1475","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"80142123","nameIdentifierScheme":"金沢大学研究者情報","nameIdentifierURI":"http://ridb.kanazawa-u.ac.jp/public/detail.php?kaken=80142123"},{"nameIdentifier":"80142123","nameIdentifierScheme":"研究者番号","nameIdentifierURI":"https://nrid.nii.ac.jp/nrid/1000080142123"}]},{"creatorNames":[{"creatorName":"Kimura, Kazuko"}],"nameIdentifiers":[{"nameIdentifier":"76136","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"80324094","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=80324094"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-10-04"}],"displaytype":"detail","filename":"PH-PR-YOSHIDA-N-13.pdf","filesize":[{"value":"446.6 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"PH-PR-YOSHIDA-N-13.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/15104/files/PH-PR-YOSHIDA-N-13.pdf"},"version_id":"d16410ea-c2c1-4d85-a6fd-4935e67a4ae3"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"A cross-sectional investigation of the quality of selected medicines in Cambodia in 2010.","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"A cross-sectional investigation of the quality of selected medicines in Cambodia in 2010."}]},"item_type_id":"4","owner":"3","path":["4312"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-10-04"},"publish_date":"2017-10-04","publish_status":"0","recid":"15104","relation_version_is_last":true,"title":["A cross-sectional investigation of the quality of selected medicines in Cambodia in 2010."],"weko_creator_id":"3","weko_shared_id":3},"updated":"2024-06-27T01:20:32.650604+00:00"}