@article{oai:kanazawa-u.repo.nii.ac.jp:00015130, author = {Somei, Masanori and Teranishi, Sakiko and Yamada, Koji and Yamada, Fumio}, issue = {9}, journal = {Chemical and Pharmaceutical Bulletin}, month = {Jan}, note = {Serotonins were found to produce 3, 4, 5, 6-tetrahydro-7-hydroxy-1H-azepino[5, 4, 3-cd]indoles by simple heating with amines under an oxygen atmosphere. Serotonins also reacted with various aldehydes to provide 3, 4, 5, 6-tetrahydro-7-hydroxy-1H-azepino[5, 4, 3-cd]indoles rather than β-carbolines under basic conditions. In these novel reactions, the presence of the 5-hydroxy group on the indole nucleus was suggested to be essential. Possible mechanisms are discussed.}, pages = {1159--1165}, title = {The Chemistry of Indoles. CVII. A Novel Synthesis of 3, 4, 5, 6-Tetrahydro-7-hydroxy-1H-azepino[5, 4, 3-cd]indoles and a New Finding on Pictet-Spengler Reaction}, volume = {49}, year = {2001} }