@article{oai:kanazawa-u.repo.nii.ac.jp:00015407,
 author = {Yamamoto, Atsushi and Kawai, Mio and Sakamoto, Mitsunori and Kodama, Shuji and Hayakawa, Kazuichi},
 issue = {3},
 journal = {Analytical Sciences},
 month = {Mar},
 note = {A sensitive and variable-wavelength optical rotatory (OR) detector for high-performance liquid chromatography is presented. This design is entirely different from that of conventional OR detectors consisting of a crossed polarizer pair. By placing a polarizing prism and a retardation plate into a commercial circular dichroism (CD) detector, the OR signal was obtained. The Mueller matrix approach was used to prove the principle of the OR signal appearance. Sugars and 4-androstene-3,17-dione were chosen as test compounds. The limit of detection was below 0.5 μg of injected sucrose at 260 nm, which was superior to that obtained with a conventional OR detector. For 4-androstene-3,17-dione, which is CD active, and shows a large anomalous OR dispersion curve, our detector gave a large OR signal with approximately half the intensity of the CD signal at 340 nm. 2008 © The Japan Society for Analytical Chemistry.},
 pages = {361--364},
 title = {An optical rotatory detector for high-performance liquid chromatography using polarization modulation},
 volume = {24},
 year = {2008}
}