@article{oai:kanazawa-u.repo.nii.ac.jp:00016081,
 author = {田中, 正二 and 河原, 榮 and 中川, 敬夫},
 issue = {2},
 journal = {金沢大学つるま保健学会誌 = Journal of the Tsuruma Health Science Society, Kanazawa University},
 month = {Jan},
 note = {The role of hepatocyte growth factor （HGF）-induced activation （phosphorylation） of its receptor, c-Met, and subsequent downstream signaling during muscle regeneration has not yet been adequately determined. We examined HGF and phospho-c-Met expression and localization during the expansion phase and time course of satellite cell activation, which is critical for muscle regeneration after injury. HGF, c-Met, myogenic differentiation 1 （MyoD）, and myogenin mRNA levels were significantly increased during muscle regeneration after injury. Phospho-c-Met was localized on the surface of regenerating muscle cells. HGF was colocalized in the same cells as phospho-c-Met, MyoD, or myogenin. The muscle area occupied by HGF-, phospho-c-Met-, MyoD-, or myogenin-positive cells expanded along with expansion of regenerating muscle. Thus, c-Met is expressed in regenerating muscle cells immediately after injury, and its kinase activity is likely activated by HGF expressed by the same cells, suggesting that HGF and c-Met contribute to myogenesis in vivo.},
 pages = {85--94},
 title = {肝細胞増殖因子の発現は骨格筋再生領域の拡大と同期する},
 volume = {39},
 year = {2016}
}