{"created":"2023-07-27T06:31:38.893403+00:00","id":17147,"links":{},"metadata":{"_buckets":{"deposit":"ad87b482-1412-43a2-8252-d9bc7d63ae17"},"_deposit":{"created_by":3,"id":"17147","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"17147"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00017147","sets":["1132:1137:1270:1322"]},"author_link":["30835"],"item_7_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2002-12-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"6","bibliographicPageEnd":"361","bibliographicPageStart":"348","bibliographicVolumeNumber":"111","bibliographic_titles":[{"bibliographic_title":"金沢大学十全医学会雑誌"}]}]},"item_7_description_16":{"attribute_name":"その他の識別子","attribute_value_mlt":[{"subitem_description":"2003249189","subitem_description_type":"Other"}]},"item_7_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"ラット脳幹内顔面神経膝部軸索損傷モデルにおける顔面神経核の逆行性変性機構の抑制に関して検討した.方法は,成熟ラットの顔面神経軸索を茎乳突孔出口で切断した末梢損傷群,同部で引き抜きより中枢側で損傷を加えた引き抜き損傷群,定位脳的に脳幹内顔面神経膝部を切断した脳幹内損傷群群,脳幹内軸索損傷後直ちに自家坐骨神経移植した坐骨神経移植群を作製し,神経細胞の生存率,周辺のグリア細胞の反応を検討した.術後7日,28日目の顔面神経細胞生存率は,末梢損傷群でそれぞれ102.4%,90.2%,引き抜き損傷群で94.6%,49.7%,脳幹内損傷群で30.9%,2.3%,移植群で43.7%,20.4%であり,移植群では逆行性変性は有意に抑制された.グリア線維性酸性蛋白(GFAP)陽性アストロサイトの発現は各群間で差はなく,ED1陽性マイクログリアおよびマクロファージの発現は末梢損傷群に比し他の3群でより顕著であった","subitem_description_type":"Abstract"}]},"item_7_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"原著論文","subitem_description_type":"Other"}]},"item_7_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学大学院医学系研究科脳医科学専攻脳機能制御学","subitem_description_type":"Other"}]},"item_7_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AN00044397","subitem_source_identifier_type":"NCID"}]},"item_7_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0022-7226","subitem_source_identifier_type":"ISSN"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"増谷, 剛"}],"nameIdentifiers":[{"nameIdentifier":"30835","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-10-04"}],"displaytype":"detail","filename":"C0000002237-012-masutani.pdf","filesize":[{"value":"8.2 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"C0000002237-012-masutani.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/17147/files/C0000002237-012-masutani.pdf"},"version_id":"e8be93b5-1963-425a-8fef-a50f785b6946"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Schwann細胞","subitem_subject_scheme":"Other"},{"subitem_subject":"逆行変性(実験的,病理学,移植)","subitem_subject_scheme":"Other"},{"subitem_subject":"坐骨神経","subitem_subject_scheme":"Other"},{"subitem_subject":"神経膠","subitem_subject_scheme":"Other"},{"subitem_subject":"ニューロン","subitem_subject_scheme":"Other"},{"subitem_subject":"Wistarラット","subitem_subject_scheme":"Other"},{"subitem_subject":"顔面神経損傷(実験的,病理学,移植)","subitem_subject_scheme":"Other"},{"subitem_subject":"軸索切断(実験的,病理学,移植)","subitem_subject_scheme":"Other"},{"subitem_subject":"神経移植脳幹疾患(実験的,病理学,移植)","subitem_subject_scheme":"Other"},{"subitem_subject":"ラット","subitem_subject_scheme":"Other"},{"subitem_subject":"動物","subitem_subject_scheme":"Other"},{"subitem_subject":"オス","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"ラット脳幹内顔面神経膝部軸索損傷モデルにおける顔面神経核の逆行性変性機構の抑制に関する研究","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ラット脳幹内顔面神経膝部軸索損傷モデルにおける顔面神経核の逆行性変性機構の抑制に関する研究"}]},"item_type_id":"7","owner":"3","path":["1322"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-10-04"},"publish_date":"2017-10-04","publish_status":"0","recid":"17147","relation_version_is_last":true,"title":["ラット脳幹内顔面神経膝部軸索損傷モデルにおける顔面神経核の逆行性変性機構の抑制に関する研究"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-07-28T00:07:28.638440+00:00"}