{"created":"2023-07-27T06:31:53.521991+00:00","id":17487,"links":{},"metadata":{"_buckets":{"deposit":"221cfa24-9a74-4801-a3d7-fd3e1d61d217"},"_deposit":{"created_by":3,"id":"17487","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"17487"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00017487","sets":["1132:1137:1270:1353"]},"author_link":["31096"],"item_7_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1996-10-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"5","bibliographicPageEnd":"672","bibliographicPageStart":"658","bibliographicVolumeNumber":"105","bibliographic_titles":[{"bibliographic_title":"金沢大学十全医学会雑誌"}]}]},"item_7_description_16":{"attribute_name":"その他の識別子","attribute_value_mlt":[{"subitem_description":"1997109872","subitem_description_type":"Other"}]},"item_7_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"家兎摘出大腿動脈を用い,5HT, NE, 高Kの血管収縮反応に及ぼすインスリンの影響を内皮の有無により比較し,更に,内皮温存標本においてアスピリン及びL-NAMEのインスリン作用への影響及びAchとSPによる内皮依存性拡張反応に対するインスリンの作用を検討した. 1)インスリンは,内皮剥離標本において濃度依存性に,5HT, NE, 高Kの収縮を抑制した. 2)インスリンにより内皮温存標本でも収縮物質に関わらず,非特異的な収縮抑制を示したが,内皮剥離標本に比べ血管収縮抑制の程度は大きかった. 3)内皮温存標本での,インスリンの血管拡張作用はアスピリン投与により変化しなかった. 4)内皮温存標本での,インスリンの血管拡張作用はL-NAME投与により収縮物質に関わらず,非特異的に抑制された. 5)インスリンによりAch及びSPの内皮依存性血管拡張反応が増強した","subitem_description_type":"Abstract"}]},"item_7_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学 医 第1内科","subitem_description_type":"Other"}]},"item_7_publisher_17":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"金沢大学十全医学会"}]},"item_7_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AN00044397","subitem_source_identifier_type":"NCID"}]},"item_7_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0022-7226","subitem_source_identifier_type":"ISSN"}]},"item_7_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"清川, 裕明"}],"nameIdentifiers":[{"nameIdentifier":"31096","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-10-04"}],"displaytype":"detail","filename":"AN00044397-105-062.pdf","filesize":[{"value":"2.1 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"AN00044397-105-062.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/17487/files/AN00044397-105-062.pdf"},"version_id":"28d51cda-ce61-47e0-95f3-f9a55f11471a"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Insulin(薬理学)","subitem_subject_scheme":"Other"},{"subitem_subject":"血管拡張(薬物影響)","subitem_subject_scheme":"Other"},{"subitem_subject":"血管内皮","subitem_subject_scheme":"Other"},{"subitem_subject":"ウサギ","subitem_subject_scheme":"Other"},{"subitem_subject":"動物","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"インスリンの内皮依存性血管拡張作用に関する検討","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"インスリンの内皮依存性血管拡張作用に関する検討"}]},"item_type_id":"7","owner":"3","path":["1353"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-10-04"},"publish_date":"2017-10-04","publish_status":"0","recid":"17487","relation_version_is_last":true,"title":["インスリンの内皮依存性血管拡張作用に関する検討"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-07-28T00:02:39.359320+00:00"}