{"created":"2023-07-27T06:31:54.332411+00:00","id":17505,"links":{},"metadata":{"_buckets":{"deposit":"e254c0eb-d13d-4ee8-a587-5682dee8e5cb"},"_deposit":{"created_by":3,"id":"17505","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"17505"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00017505","sets":["1132:1137:1270:1355"]},"author_link":["28911"],"item_7_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1996-06-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"461","bibliographicPageStart":"450","bibliographicVolumeNumber":"105","bibliographic_titles":[{"bibliographic_title":"金沢大学十全医学会雑誌"}]}]},"item_7_description_16":{"attribute_name":"その他の識別子","attribute_value_mlt":[{"subitem_description":"1997037478","subitem_description_type":"Other"}]},"item_7_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"1)放射線誘発アポトーシスは小細胞癌細胞株であるSBC-1, SBC-3に発現し,その最大発現頻度はSBC-1において10Gy照射48時間後17.9±0.1%, SBC-3において20Gy照射72時間後9.6±2.3%であった. 2)放射線誘発アポトーシスの発現は照射された生検腫瘍組織においても確認された. 3)Fas抗原の発現はSBC-3及び腺癌細胞株であるRERF-LC-MSに,Bc1-2蛋白の発現は全細胞株に認められた. 4)10Gy照射後SBC-3においてFasmRNA発現の増加とそれに伴うFas抗原発現の増加があり,抗Fas抗体によるアポトーシスの誘発が促進された. 5)RERF-LC-MSでは放射線誘発アポトーシスは認められず,抗Fas抗体によるアポトーシスの誘発も認められなかった","subitem_description_type":"Abstract"}]},"item_7_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学 医 放射線医","subitem_description_type":"Other"}]},"item_7_publisher_17":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"金沢大学十全医学会"}]},"item_7_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AN00044397","subitem_source_identifier_type":"NCID"}]},"item_7_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0022-7226","subitem_source_identifier_type":"ISSN"}]},"item_7_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"高仲, 強"}],"nameIdentifiers":[{"nameIdentifier":"28911","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"00216673","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=00216673"},{"nameIdentifier":"00216673","nameIdentifierScheme":"研究者番号","nameIdentifierURI":"https://nrid.nii.ac.jp/nrid/1000000216673"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-10-04"}],"displaytype":"detail","filename":"AN00044397-105-042.pdf","filesize":[{"value":"2.5 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"AN00044397-105-042.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/17505/files/AN00044397-105-042.pdf"},"version_id":"a4204fc6-21e0-49a5-879b-fca0346cbb83"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"研究","subitem_subject_scheme":"Other"},{"subitem_subject":"細胞","subitem_subject_scheme":"Other"},{"subitem_subject":"蛋白質","subitem_subject_scheme":"Other"},{"subitem_subject":"肺腫瘍(悪性,抗原・抗体・補体)","subitem_subject_scheme":"Other"},{"subitem_subject":"放射線障害","subitem_subject_scheme":"Other"},{"subitem_subject":"bcl-2癌原遺伝子蛋白質","subitem_subject_scheme":"Other"},{"subitem_subject":"Fas抗原","subitem_subject_scheme":"Other"},{"subitem_subject":"アポトーシス","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"肺癌細胞における放射線誘発アポトーシスの研究　Fas抗原及びBcl-2蛋白との関連","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"肺癌細胞における放射線誘発アポトーシスの研究　Fas抗原及びBcl-2蛋白との関連"}]},"item_type_id":"7","owner":"3","path":["1355"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-10-04"},"publish_date":"2017-10-04","publish_status":"0","recid":"17505","relation_version_is_last":true,"title":["肺癌細胞における放射線誘発アポトーシスの研究　Fas抗原及びBcl-2蛋白との関連"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-07-28T00:02:22.967239+00:00"}