{"created":"2023-07-27T06:31:55.347822+00:00","id":17529,"links":{},"metadata":{"_buckets":{"deposit":"d95c3d93-cd12-47a5-8968-3f0cc11749bc"},"_deposit":{"created_by":3,"id":"17529","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"17529"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00017529","sets":["1132:1137:1270:1357"]},"author_link":["31127"],"item_7_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1996-02-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"80","bibliographicPageStart":"71","bibliographicVolumeNumber":"105","bibliographic_titles":[{"bibliographic_title":"金沢大学十全医学会雑誌"}]}]},"item_7_description_16":{"attribute_name":"その他の識別子","attribute_value_mlt":[{"subitem_description":"1996227026","subitem_description_type":"Other"}]},"item_7_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"サーファクタントの作成に必要な脂質の種類と割合を検討する為,種々の合成リン脂質の組合わせと蛋白質からなる再構築サーファクタントを作成して,生物学的及び物理学的活性を調べた. 1)疎水性蛋白質であるSP-BとSP-Cはサーファクタントの活性に不可欠な因子である. 2)サーファクタントの脂質として,飽和脂肪鎖を持つDPPCだけでは不十分である. 3)酸性リン脂質であるPGはサーファクタントの活性発現に必要な脂質である.サーファクタントの全脂質に対するPGの割合としては15～20%が適当であると考えられる. 4)不飽和脂肪鎖をもつu-PCはサーファクタントの動的条件下における性能を高め,換気量を増加させる為に必要な物質である.DPPC, PG,及びu-PC(重量比,60:20:20)を混合して作成したサーファクタントは,天然肺サーファクタントとほぼ同様の活性を示した","subitem_description_type":"Abstract"}]},"item_7_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学 医 麻酔蘇生","subitem_description_type":"Other"}]},"item_7_publisher_17":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"金沢大学十全医学会"}]},"item_7_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AN00044397","subitem_source_identifier_type":"NCID"}]},"item_7_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0022-7226","subitem_source_identifier_type":"ISSN"}]},"item_7_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"高橋, 麗子"}],"nameIdentifiers":[{"nameIdentifier":"31127","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-10-04"}],"displaytype":"detail","filename":"AN00044397-105-007.pdf","filesize":[{"value":"1.4 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"AN00044397-105-007.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/17529/files/AN00044397-105-007.pdf"},"version_id":"dfbf262c-80d2-4522-8ce9-bf25f9349a8d"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"脂質","subitem_subject_scheme":"Other"},{"subitem_subject":"肺サーファクタント","subitem_subject_scheme":"Other"},{"subitem_subject":"ウサギ","subitem_subject_scheme":"Other"},{"subitem_subject":"動物","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"サーファクタントの生理的活性に必要な脂質の種類の検討","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"サーファクタントの生理的活性に必要な脂質の種類の検討"}]},"item_type_id":"7","owner":"3","path":["1357"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-10-04"},"publish_date":"2017-10-04","publish_status":"0","recid":"17529","relation_version_is_last":true,"title":["サーファクタントの生理的活性に必要な脂質の種類の検討"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-07-28T00:02:01.609429+00:00"}