{"created":"2023-07-27T06:31:56.448014+00:00","id":17555,"links":{},"metadata":{"_buckets":{"deposit":"8e5cfab1-344b-4ce4-8769-330375044ea9"},"_deposit":{"created_by":3,"id":"17555","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"17555"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00017555","sets":["1132:1137:1270:1359"]},"author_link":["23157"],"item_7_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1995-10-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"5","bibliographicPageEnd":"540","bibliographicPageStart":"529","bibliographicVolumeNumber":"104","bibliographic_titles":[{"bibliographic_title":"金沢大学十全医学会雑誌"}]}]},"item_7_description_16":{"attribute_name":"その他の識別子","attribute_value_mlt":[{"subitem_description":"1996163466","subitem_description_type":"Other"}]},"item_7_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"L-グルタミン酸に対する電流応答をパッチクランプ法を用いて研究した. 1)1196個の双極細胞のうち119個が膜電位を-46mVに保持した場合にグルタミン酸に対して内向きの電流応答を生じ,応答を生じた細胞はOFF型双極細胞の形態学的特徴を持っていた. 2)OFF型双極細胞のグルタミン酸に対する応答はグルタミン酸の濃度に依存して増大し,100μMのグルタミン酸で応答は飽和し,それ以上の濃度では脱感作を示した. 3)OFF型双極細胞のグルタミン酸に対する感受性は細胞の各部位のうち樹状突起部で最も高かった. 4)20μMのカイニン酸と100μMのAMPAはグルタミン酸を投与した場合に類似した作用を示した. 5)グルタミン酸が活性化するチャネルはアルカリ金属イオンに対し低い選択性を示し,Na+, K+, Cs+及びCa2+に対し透過性を示した","subitem_description_type":"Abstract"}]},"item_7_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学 医 眼科","subitem_description_type":"Other"}]},"item_7_publisher_17":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"金沢大学十全医学会"}]},"item_7_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AN00044397","subitem_source_identifier_type":"NCID"}]},"item_7_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0022-7226","subitem_source_identifier_type":"ISSN"}]},"item_7_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"佐々木, 次壽"}],"nameIdentifiers":[{"nameIdentifier":"23157","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"00338188","nameIdentifierScheme":"研究者番号","nameIdentifierURI":"https://nrid.nii.ac.jp/nrid/1000000338188"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-10-04"}],"displaytype":"detail","filename":"AN00044397-104-051.pdf","filesize":[{"value":"1.8 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"AN00044397-104-051.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/17555/files/AN00044397-104-051.pdf"},"version_id":"ad44a996-da47-41fe-bdf6-351dca496068"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Glutamates","subitem_subject_scheme":"Other"},{"subitem_subject":"細胞","subitem_subject_scheme":"Other"},{"subitem_subject":"神経伝達物質","subitem_subject_scheme":"Other"},{"subitem_subject":"ネコ","subitem_subject_scheme":"Other"},{"subitem_subject":"網膜","subitem_subject_scheme":"Other"},{"subitem_subject":"ネコ","subitem_subject_scheme":"Other"},{"subitem_subject":"動物","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"ネコ網膜OFF型双極細胞のグルタミン酸応答に関する研究","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ネコ網膜OFF型双極細胞のグルタミン酸応答に関する研究"}]},"item_type_id":"7","owner":"3","path":["1359"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-10-04"},"publish_date":"2017-10-04","publish_status":"0","recid":"17555","relation_version_is_last":true,"title":["ネコ網膜OFF型双極細胞のグルタミン酸応答に関する研究"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-07-28T00:01:38.681961+00:00"}