{"created":"2023-07-27T06:31:56.575284+00:00","id":17558,"links":{},"metadata":{"_buckets":{"deposit":"7eb11481-092f-4850-904f-e13077e73bd2"},"_deposit":{"created_by":3,"id":"17558","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"17558"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00017558","sets":["1132:1137:1270:1359"]},"author_link":["31146"],"item_7_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1995-10-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"5","bibliographicPageEnd":"562","bibliographicPageStart":"556","bibliographicVolumeNumber":"104","bibliographic_titles":[{"bibliographic_title":"金沢大学十全医学会雑誌"}]}]},"item_7_description_16":{"attribute_name":"その他の識別子","attribute_value_mlt":[{"subitem_description":"1996154360","subitem_description_type":"Other"}]},"item_7_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"心筋症ハムスターの4代継代培養心筋線維芽細胞を3H-プロリンで標識してコラーゲン合成能を量的,質的に検討した.心筋症ハムスターとしてBio14.6,対照として正常ハムスター(F1b)を用いた.Bio14.6培養心筋線維芽細胞の総コラーゲン合成量とコラーゲン合成比は13週齢から25週齢にかけて増加し,25週齢のそれは13週齢のBio14.6及び25週齢のF1bより有意に大であった.質的には,Bio14.6では13週齢,25週齢共にF1bと比べてIII型,V型合成比率が大きく,13週齢より25週齢にかけてI型が減少し,III型,V型コラーゲンが増加した.カプトプリル添加により25週齢のBio14.6の総コラーゲン合成量は有意に減少した.以上より,Bio14.6培養心筋線維芽細胞におけるコラーゲン代謝異常が認められ,カプトプリルがそのコラーゲン代謝を改善することが証明された","subitem_description_type":"Abstract"}]},"item_7_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学 医 第2内科","subitem_description_type":"Other"}]},"item_7_publisher_17":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"金沢大学十全医学会"}]},"item_7_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AN00044397","subitem_source_identifier_type":"NCID"}]},"item_7_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0022-7226","subitem_source_identifier_type":"ISSN"}]},"item_7_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"篠原, 豪秀"}],"nameIdentifiers":[{"nameIdentifier":"31146","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-10-04"}],"displaytype":"detail","filename":"AN00044397-104-054.pdf","filesize":[{"value":"1.2 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"AN00044397-104-054.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/17558/files/AN00044397-104-054.pdf"},"version_id":"35e66357-7a10-4869-9796-a8fea73334f7"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Angiotensin-Converting Enzyme Inhibitors","subitem_subject_scheme":"Other"},{"subitem_subject":"Collagen","subitem_subject_scheme":"Other"},{"subitem_subject":"Peptidyl-Dipeptidase A","subitem_subject_scheme":"Other"},{"subitem_subject":"酵素阻害剤","subitem_subject_scheme":"Other"},{"subitem_subject":"心筋疾患(実験的)","subitem_subject_scheme":"Other"},{"subitem_subject":"心筋","subitem_subject_scheme":"Other"},{"subitem_subject":"線維芽細胞","subitem_subject_scheme":"Other"},{"subitem_subject":"ハムスター類","subitem_subject_scheme":"Other"},{"subitem_subject":"ハムスター","subitem_subject_scheme":"Other"},{"subitem_subject":"動物","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"心筋症ハムスターの培養心筋線維芽細胞におけるコラーゲン合成能とそれに及ぼすアンジオテンシン変換酵素阻害薬の影響","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"心筋症ハムスターの培養心筋線維芽細胞におけるコラーゲン合成能とそれに及ぼすアンジオテンシン変換酵素阻害薬の影響"}]},"item_type_id":"7","owner":"3","path":["1359"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-10-04"},"publish_date":"2017-10-04","publish_status":"0","recid":"17558","relation_version_is_last":true,"title":["心筋症ハムスターの培養心筋線維芽細胞におけるコラーゲン合成能とそれに及ぼすアンジオテンシン変換酵素阻害薬の影響"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-07-28T00:01:35.399816+00:00"}