{"created":"2023-07-27T06:31:58.389650+00:00","id":17601,"links":{},"metadata":{"_buckets":{"deposit":"b176fa25-45c7-4e16-a79b-3cae3182bd9a"},"_deposit":{"created_by":3,"id":"17601","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"17601"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00017601","sets":["1132:1137:1270:1363"]},"author_link":["31180"],"item_7_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1995-02-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"142","bibliographicPageStart":"132","bibliographicVolumeNumber":"104","bibliographic_titles":[{"bibliographic_title":"金沢大学十全医学会雑誌"}]}]},"item_7_description_16":{"attribute_name":"その他の識別子","attribute_value_mlt":[{"subitem_description":"1996021707","subitem_description_type":"Other"}]},"item_7_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"生後初めて発熱を認めた乳幼児を対象にした. 1)血液細胞より得たDNAのPCR産物をエチジウムブロマイド染色にて判定したところ,血中HHV-6DNAは生後初めて発熱を認めた乳幼児の約40%に検出され,その約65%に突発性発疹症に典型的な解熱後発疹がみられた. 2)血中HHV-6DNA陽性者は抗HHV-6IgG抗体が全例検出されず,ペア血清の検討からも,HHV-6初感染と考えられた.血中HHV-6DNA陰性者では一部に抗HHV-6IgG抗体が陰性で,解熱後発疹や回復期に抗HHV-6IgG抗体の上昇をみるHHV-6初感染例が含まれていた. 3)血中HHV-6DNA陽性者をHHV-6初感染として,リンパ球サブセットを検索した.リンパ球サブセット比は非HHV-6感染例と大きな違いはなかったが,HHV-6初感染でとりわけNK細胞における早期活性化抗原であるCD69抗原発現が顕著であった","subitem_description_type":"Abstract"}]},"item_7_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学 医 小児科","subitem_description_type":"Other"}]},"item_7_publisher_17":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"金沢大学十全医学会"}]},"item_7_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AN00044397","subitem_source_identifier_type":"NCID"}]},"item_7_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0022-7226","subitem_source_identifier_type":"ISSN"}]},"item_7_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"新谷, 尚久"}],"nameIdentifiers":[{"nameIdentifier":"31180","nameIdentifierScheme":"WEKO"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-10-04"}],"displaytype":"detail","filename":"AN00044397-104-013.pdf","filesize":[{"value":"1.7 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"AN00044397-104-013.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/17601/files/AN00044397-104-013.pdf"},"version_id":"f0eca7a8-5c1d-4fb8-82ad-d63d25817cf1"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"ヘルペスウイルス科","subitem_subject_scheme":"Other"},{"subitem_subject":"ヒトヘルペスウイルス6型","subitem_subject_scheme":"Other"},{"subitem_subject":"ヘルペスウイルス科感染症(免疫学)","subitem_subject_scheme":"Other"},{"subitem_subject":"アレルギーと免疫学","subitem_subject_scheme":"Other"},{"subitem_subject":"感染","subitem_subject_scheme":"Other"},{"subitem_subject":"研究","subitem_subject_scheme":"Other"},{"subitem_subject":"乳児","subitem_subject_scheme":"Other"},{"subitem_subject":"ヒト","subitem_subject_scheme":"Other"},{"subitem_subject":"ヒト","subitem_subject_scheme":"Other"},{"subitem_subject":"乳児(1～23ヶ月)","subitem_subject_scheme":"Other"},{"subitem_subject":"幼児(2～5)","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"departmental bulletin paper","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"乳幼児におけるヒトヘルペスウイルス-6(HHV-6)初感染の臨床免疫学的研究","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"乳幼児におけるヒトヘルペスウイルス-6(HHV-6)初感染の臨床免疫学的研究"}]},"item_type_id":"7","owner":"3","path":["1363"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-10-04"},"publish_date":"2017-10-04","publish_status":"0","recid":"17601","relation_version_is_last":true,"title":["乳幼児におけるヒトヘルペスウイルス-6(HHV-6)初感染の臨床免疫学的研究"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-07-28T00:00:57.981782+00:00"}