@article{oai:kanazawa-u.repo.nii.ac.jp:00026625,
 author = {Nakajima, Kenichi and Kawano, Masaya and Kinami, Shinichi and Fujimura, Takashi and Miwa, Koichi and Tonami, Norihisa},
 issue = {3},
 journal = {Annals of Nuclear Medicine},
 month = {May},
 note = {Objective: The physiology of gastrointestinal transfer function after proximal gastrectomy with bypass-tract reconstruction is not well understood. We applied a simultaneous dual-radionuclide method with a hepatobiliary imaging and gastric emptying study to evaluate physiologic alterations occurring after surgery. Methods: Nineteen patients with early gastric cancer, including 9 preoperative control patients and 10 who had proximal gastrectomy and double-tract reconstruction surgery were examined by dual-radionuclide hepatobiliary and gastric emptying studies (99mTc PMT and 111In DTPA). Retention fraction in the stomach at 3 minutes (R3) and 60 minutes (R60) and gastric emptying half-time (GET) were calculated. Bile reflux and mixture of bile and food were also evaluated. Results: The retention fractions of R3 and R60 were significantly lower in the double-tract reconstruction group than those in the preoperative group. GET differed significantly between the double-tract and preoperative groups (20.7 min ± 7.1 min and 36.2 min ± 11.0 min, p = 0.0018). The mixture of bile and food was not good in the double-tract reconstruction group (p = 0.014 vs. preoperative). Patients with a large residual stomach showed slower initial emptying (p = 0.0068) and a better mixture of bile and food (p = 0.058) compared to those with a small residual stomach. The bile reflux was not significantly increased after surgery. Conclusion: The dual-radionuclide gastrointestinal and hepatobiliary imaging was feasible and could demonstrate characteristic transit patterns of the foods and bile in the double-tract reconstruction procedure. A larger residual stomach, if possible, is desirable to provide better transfer and mixing of bile and foods., 金沢大学医学部附属病院核医学診療科, 木南, 伸一},
 pages = {185--191},
 title = {Dual-radionuclide simultaneous gastric emptying and bile transit study after gastric surgery with double-tract reconstruction},
 volume = {19},
 year = {2005}
}