@article{oai:kanazawa-u.repo.nii.ac.jp:00026651, author = {高田, 佳子 and 山下, 竜也 and 島谷, 明義 and 飯田, 宗穂 and 荒井, 邦明 and 北村, 和哉 and 加賀谷, 尚史 and 山下, 太郎 and 酒井, 佳夫 and 中本, 安成 and 本多, 政夫 and 金子, 周一 and 小山, 有}, issue = {6}, journal = {Acta Hepatologica Japonica}, month = {Jan}, note = {Case is 60 year-old-man who had been followed up about liver injury and diabetes mellitus in another clinic from 1990. He visited our hospital suffering from epigastralgia in October 2003, and admitted with the finding of hemobilia pointed out by upper GI examination. We diagnosed the illness as hepatocellular carcinoma with hemobilia, because of multiple tumors in the right lobe of the liver, portal vein thrombus, and the elevation of tumor markers such as alpha-fetoprotein (AFP), protein induced by vitamin-K absence (PIVKA-II) and AFP L3 fraction with alcoholic liver cirrhosis. He was treated with combination therapy consisting of hepatic arterial chemotherapy and injection of Interferon-ホア, and done as an outpatient after the first course treatment. The biliary infection was aggravated during the 4th course, and died 8 months after the initial diagnosis. It is said that hepatocellular carcinoma diagnosed incidentally with hemobilia is relatively rare and that prognosis is poor. In spite of the absence of decrease in tumor on imaging, this case can be considered as one in which this patient got the more prolongud life by interferon combined hepatic arterial chemotherapy., 金沢大学医学部附属病院内科(旧第一内科)}, pages = {365--371}, title = {胆道出血を契機に発見され,動注化学療法を行った肝細胞癌の1例}, volume = {46}, year = {2005} }