@article{oai:kanazawa-u.repo.nii.ac.jp:00026950,
 author = {見崎, 孝一 and 内山, 尚之 and 南部, 育 and 会田, 泰裕 and 上出, 智也 and 毛利, 正直 and 植田, 文明 and 中田, 光俊 and Misaki, Kouichi and Uchiyama, Naoyuki and Nambu, Iku and Aida, Yasuhiro and Kamide, Tomoya and Mohri, Masanao and Ueda, Fumiaki and Nakada, Mitsutoshi},
 journal = {World Neurosurgery},
 month = {Jun},
 note = {Background: During endovascular treatment of an aneurysm, the importance of the initial coil volume for facilitating tight packing is unclear. We retrospectively studied the relationships between initial packing density (PD; initial coil volume divided by aneurysm volume), final PD (volume of all coils divided by aneurysm volume). Methods: We reviewed 105 aneurysms in 98 patients who underwent endovascular coiling between April 2011 and March 2014. The initial coil was defined as the first coil in the single-catheter method and the first 2 coils in the double-catheter method. The patient data were divided into groups with or without a final PD ≥20%, and the significant predictors of a final PD ≥20% were determined using multivariable logistic regression. The optimal cutoff value for the initial PD was determined using a receiver operating characteristic curve. Results: Of 105 aneurysms, 56 and 49 were treated with single- and double-catheter methods, respectively. Statistically significant differences in rupture status, neck size, dome/neck ratio, and initial PD were observed between aneurysms with and without a final PD ≥20% (all P < 0.05). Multivariate analysis showed that initial PD (P = 0.025; odds ratio, 1.22) and rupture status (P = 0.002; odds ratio, 0.19) were significantly associated with a final PD ≥20%. Using receiver operating characteristic curve analysis, the cutoff points of initial PD to achieve a final PD ≥20% were 8.0% and 10.0% in single- and double-catheter groups, respectively. Conclusions: Initial PD appears to be a critical factor for achieving tight packing. © 2016 Elsevier Inc. All rights reserved., Embargo Period 12 months},
 pages = {397--402},
 title = {Optimizing the Volume of the Initial Framing Coil to Facilitate Tight Packing of Intracranial Aneurysms},
 volume = {90},
 year = {2016}
}