{"created":"2023-07-27T06:38:47.547499+00:00","id":26986,"links":{},"metadata":{"_buckets":{"deposit":"b951f5df-a345-4390-988d-c2addcd754c2"},"_deposit":{"created_by":3,"id":"26986","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"26986"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00026986","sets":["1761:1762:1763"]},"author_link":["45706","20204","266","25495","45705","389","20099","45707","273","45708"],"item_4_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2000-03-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"3","bibliographicPageEnd":"404","bibliographicPageStart":"399","bibliographicVolumeNumber":"41","bibliographic_titles":[{"bibliographic_title":"Japanese Heart Journal"}]}]},"item_4_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Familial long QT syndrome (LQTS) is caused by mutations in genes encoding ion channels important in determining ventricular repolarization. Mutations in at least five genes have been associated with the LQTS. Fire genes, KCNQ1, HERG, SCN5A, KCNE1, and KCNE2, have been identified. We have identified a missense mutation in the HERG gene in identical twins in a Japanese family with LQTS. The identical twins in our study had QT prolongation and the same missense mutation. However only the proband had a history of syncope. Although many mutations in LQT genes have been reported, there are few reports of twins with LQTS. This is the first report, to our knowledge, of identical twins with a HERG gene mutation.","subitem_description_type":"Abstract"}]},"item_4_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学附属病院検査部","subitem_description_type":"Other"}]},"item_4_publisher_17":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Japanese Heart Journal Association"}]},"item_4_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1536/jhj.41.399","subitem_relation_type_select":"DOI"}}]},"item_4_rights_23":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Copyright (c) 2000 by the Japanese Heart Journal"}]},"item_4_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AA00690786","subitem_source_identifier_type":"NCID"}]},"item_4_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0021-4868","subitem_source_identifier_type":"ISSN"}]},"item_4_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Hayashi, Kenshi"}],"nameIdentifiers":[{},{},{},{}]},{"creatorNames":[{"creatorName":"Shimizu, Masami"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Ino, Hidekazu"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Okeie, Kazuyasu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yamaguchi, Masato"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"Yasuda, Toshihiko"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Fujino, Noboru"}],"nameIdentifiers":[{},{},{},{}]},{"creatorNames":[{"creatorName":"Fujii, Hiroyuki"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Fujita, Shinichiro"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Mabuchi, Hiroshi"}],"nameIdentifiers":[{},{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-10-05"}],"displaytype":"detail","filename":"HO-PR-HAYASHI-K-399.pdf","filesize":[{"value":"130.5 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"HO-PR-HAYASHI-K-399.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/26986/files/HO-PR-HAYASHI-K-399.pdf"},"version_id":"196ef636-9b69-4f8f-8407-7d61992724bb"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Identical Twins with Long QT Syndrome Associated with a Missense Mutation in the S4 Region of the HERG","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Identical Twins with Long QT Syndrome Associated with a Missense Mutation in the S4 Region of the HERG"}]},"item_type_id":"4","owner":"3","path":["1763"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-10-05"},"publish_date":"2017-10-05","publish_status":"0","recid":"26986","relation_version_is_last":true,"title":["Identical Twins with Long QT Syndrome Associated with a Missense Mutation in the S4 Region of the HERG"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-07-27T11:49:36.420429+00:00"}