{"created":"2023-07-27T06:38:49.069133+00:00","id":27021,"links":{},"metadata":{"_buckets":{"deposit":"f5ebf9a8-7cd7-45fb-a8f5-953e368172dd"},"_deposit":{"created_by":3,"id":"27021","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"27021"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00027021","sets":["1761:1762:1763"]},"author_link":["22059","45823"],"item_4_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2002-12-20","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"6","bibliographicPageEnd":"237","bibliographicPageStart":"230","bibliographicVolumeNumber":"19","bibliographic_titles":[{"bibliographic_title":"Journal of traditional medicines = 和漢医薬学雑誌"}]}]},"item_4_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The auricular blood flow in intact rats decreased maximally at 15min after administration of Oren-gedoku-to extract (1.0/kg, intraduodenal (i.d.)), although the heart rates and the blood pressure scarcely changed. In rats pretreated intravenously with theophylline (5mg/kg), the auricular blood flow also decreased similarly after its administration, while the heart rate and the blood pressure decreased. The extract (0.35g/kg, i.d.) of Scutellariae Radix which is the main constituent of Oren-gedoku-to decreased the auricular blood flow, the heart rate, and the blood pressure. On the other hand, In rats pretreated with reserpine (5mg/kg, i.v.) 24hrs before the administration, the blood flow, heart rate and blood pressure were not hardly affected after administration of both Oren-gedoku-to and Scutellariae Radix. In the isolated right and left atria, and papillary muscle of rats, the frequency and the strength of contraction was not influenced with Oren-gedoku-to extract and its constituent plant extracts. In the isolated Langendorff's heart of rats, the left ventricular systolic maximum pressure and heart rate were not influenced with Oren-gedoku-to, although the coronary flow was slightly increased. The above results suggest that Oren-gedoku-to is useful in hotflush, because of its decreasing effects on auricular blood flow without cardiac function, and among the constituent plants of Oren-gedoku-to, Scutellariae Radix plays a main part.","subitem_description_type":"Abstract"}]},"item_4_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学附属病院薬剤部","subitem_description_type":"Other"}]},"item_4_publisher_17":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Medical and Pharmaceutical Society for WAKAN-YAKU = 和漢医薬学会"}]},"item_4_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://www.wakan-iyaku.gr.jp/index2.html","subitem_relation_type_select":"URI"}},{"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://ci.nii.ac.jp/naid/110001846576/en/","subitem_relation_type_select":"URI"}}]},"item_4_rights_23":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"本文データは和漢医薬学会の許諾に基づきCiNiiから複製したものである"}]},"item_4_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AA12035198","subitem_source_identifier_type":"NCID"}]},"item_4_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1880-1447","subitem_source_identifier_type":"ISSN"}]},"item_4_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"脇田, 広美"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"宮本, 謙一"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-10-05"}],"displaytype":"detail","filename":"PH-PR-MIAMOTO-K-230.pdf","filesize":[{"value":"866.9 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"PH-PR-MIAMOTO-K-230.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/27021/files/PH-PR-MIAMOTO-K-230.pdf"},"version_id":"92a7b173-8d97-4d09-a644-4cc81fd302c9"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"黄連解毒湯およびその構成生薬の心・血管系に対する作用 : ほてり・顔面紅潮に対する有効性の検討","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"黄連解毒湯およびその構成生薬の心・血管系に対する作用 : ほてり・顔面紅潮に対する有効性の検討"},{"subitem_title":"Effects of Oren-gedoku-to and its constituents on the cardiovascular system : Investigation of its efficacy in hotflush","subitem_title_language":"en"}]},"item_type_id":"4","owner":"3","path":["1763"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-10-05"},"publish_date":"2017-10-05","publish_status":"0","recid":"27021","relation_version_is_last":true,"title":["黄連解毒湯およびその構成生薬の心・血管系に対する作用 : ほてり・顔面紅潮に対する有効性の検討"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-07-27T21:14:44.518740+00:00"}