{"created":"2023-07-27T06:38:52.852440+00:00","id":27110,"links":{},"metadata":{"_buckets":{"deposit":"9bccc0b6-a9df-49f1-9ffa-062a72ccc3e0"},"_deposit":{"created_by":3,"id":"27110","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"27110"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00027110","sets":["1761:1762:1763"]},"author_link":["21297"],"item_4_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1998-01-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"123","bibliographicPageStart":"119","bibliographicVolumeNumber":"10","bibliographic_titles":[{"bibliographic_title":"老年消化器病 = Journal of geriatric gastroenterology"}]}]},"item_4_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"加齢に伴う凝固能の変動では, 血漿中フィブリノゲン, von Willebrand因子, 第VIII因子濃度の増加がほぼ異論のないところである. 凝固阻止因子では, 妊娠可能年齢の女性が同年齢の男性より高いが, 更年期に入ると男性が高くなることについても, ほぼ諸報告が一致している. このことは, 血小板機能をも増強している可能性があり, 老年者では若年者に比べ, 血栓症を発現しやすいことを意味している. また老年者ではこと血栓傾向に関する限り, 男性が女性よりも不利である. ただし, そのことがどの程度の臨床的意義があるのか, またなぜそのような変化を生ずるのかについては明らかではない. あるいは, 加齢による動脈硬化など血管の変化が, 上記の急性期反応性蛋白の産生亢進を生じているのかも知れない. 悪性腫瘍や手術など, 血栓傾向を呈するような場合には, 老年者では血栓を生じないような配慮が必要であるが, 抗血栓薬の投与が必要かどうかは疑問である. 老年者の消化器疾患に際して考慮すべきことは数多い.","subitem_description_type":"Abstract"}]},"item_4_publisher_17":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"老年消化器病研究討論会編 / 医学図書出版"}]},"item_4_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://www.igakutosho.co.jp/","subitem_relation_type_select":"URI"}}]},"item_4_rights_23":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Copyright © 医学図書出版 | 許可を得て登録"}]},"item_4_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AN10131385","subitem_source_identifier_type":"NCID"}]},"item_4_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0914-8590","subitem_source_identifier_type":"ISSN"}]},"item_4_text_2":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_text_value":"[特集]加齢とリスクファクター"},{"subitem_text_value":"Changes in hemostatic function with aging"}]},"item_4_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"松田, 保"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-10-05"}],"displaytype":"detail","filename":"ME-PR-MATSUDA-T-119.pdf","filesize":[{"value":"2.6 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"ME-PR-MATSUDA-T-119.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/27110/files/ME-PR-MATSUDA-T-119.pdf"},"version_id":"788bfccb-5e70-4809-a8d0-0f771ebed53f"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"加齢に伴う変化:血液凝固機能","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"加齢に伴う変化:血液凝固機能"}]},"item_type_id":"4","owner":"3","path":["1763"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-10-05"},"publish_date":"2017-10-05","publish_status":"0","recid":"27110","relation_version_is_last":true,"title":["加齢に伴う変化:血液凝固機能"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-07-27T21:13:00.249780+00:00"}