{"created":"2023-07-27T06:39:06.180956+00:00","id":27419,"links":{},"metadata":{"_buckets":{"deposit":"8e218256-43f2-476d-a587-83d542b33625"},"_deposit":{"created_by":3,"id":"27419","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"27419"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00027419","sets":["1777:1778:1779"]},"author_link":["47666","47661","47667","47663","47665","47664","47662"],"item_4_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"1984-06-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"6","bibliographicPageEnd":"1777","bibliographicPageStart":"1762","bibliographicVolumeNumber":"159","bibliographic_titles":[{"bibliographic_title":"Journal of Experimental Medicine"}]}]},"item_4_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Plasmacytomas with short latent periods can be induced in BALB/c mice by a single intraperitoneal (i.p.) injection of 0.5 ml pristane followed 20-40 d later by an injection of Abelson virus. The karyotypes of 18 such tumors were determined; 10 of these had rcpt 12;15, 5 had rcpt 6;15 and 3 had no translocations, but two of these have been shown to have interstitial deletions of chromosome 15. The specific breakpoints were the same as described in pristane-induced plasmacytomas, i.e., at 15D2/3, 6C2, and 12F2. Near diploid karyotypes and trisomy of chromosome 11 were frequently seen. All of the Abelson-plus-pristane-induced plasmacytomas (ABPC) were studied as transplanted tumors, contained integrated v-abl sequences, and actively transcribed v-abl mRNA. All but one of these tumors contained abundant myc RNA transcripts. The shortness of the latent periods of the ABPC suggests that the rcpt 12;15 and rcpt 6;15 occur soon after pristane administration and are present at the time Abelson virus is introduced. In this form of plasmacytomagenesis, activated v-abl genes appear to bypass other genetic changes that require a much longer period of time in pristane plasmacytomagenesis. Nonetheless, the consistent finding of chromosome-15 alterations and abundant myc expression in these plasmacytomas emphasize the apparent need for multiple events even in the genesis of some tumors induced by rapid transforming viruses.","subitem_description_type":"Abstract"}]},"item_4_publisher_17":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Rockefeller University Press"}]},"item_4_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1084/jem.159.6.1762","subitem_relation_type_select":"DOI"}}]},"item_4_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://jem.rupress.org/content/159/6/1762","subitem_relation_type_select":"URI"}}]},"item_4_rights_23":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 1984 Rockefeller University Press"}]},"item_4_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AA00697559","subitem_source_identifier_type":"NCID"}]},"item_4_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0022-1007","subitem_source_identifier_type":"ISSN"}]},"item_4_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Ohno, Shinsuke"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"Migita, Shunsuke"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Wiener, Francis"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Babonits, M."}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Klein, G."}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Mushinski, J. F."}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Potter, M."}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-10-05"}],"displaytype":"detail","filename":"CA-PR-OHNO-S-1762.pdf","filesize":[{"value":"1.3 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"CA-PR-OHNO-S-1762.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/27419/files/CA-PR-OHNO-S-1762.pdf"},"version_id":"079afdd1-20c2-49a6-bc8e-acd89c041b4d"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Chromosomal translocations activating myc sequences and transduction of v-abl are critical events in the rapid induction of plasmacytomas by Pristane and Abelson virus","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Chromosomal translocations activating myc sequences and transduction of v-abl are critical events in the rapid induction of plasmacytomas by Pristane and Abelson virus"}]},"item_type_id":"4","owner":"3","path":["1779"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-10-05"},"publish_date":"2017-10-05","publish_status":"0","recid":"27419","relation_version_is_last":true,"title":["Chromosomal translocations activating myc sequences and transduction of v-abl are critical events in the rapid induction of plasmacytomas by Pristane and Abelson virus"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-07-27T21:06:34.918244+00:00"}