@article{oai:kanazawa-u.repo.nii.ac.jp:00028422,
 author = {西内, 巧 and 山口, 和男 and Nishiuchi, Takumi and Masuda, Daisuke and Nakashita, Hideo and Ichimura, Kazuya and Shinozaki, Kazuo and Yoshida, Shigeo and Kimura, Makoto and Yamaguchi, Isamu and Yamaguchi, Kazuo},
 issue = {5},
 journal = {Molecular Plant-Microbe Interactions},
 month = {May},
 note = {Phytopathogenic fungi such as Fusarium spp. synthesize trichothecene family phytotoxins. Although the type B trichothecene, deoxynivalenol (DON), is thought to be a virulence factor allowing infection of plants by their trichothecene-producing Fusarium spp., little is known about effects of trichothecenes on the defense response in host plants. Therefore, in this article, we investigated these effects of various trichothecenes in Fusarium-susceptible Arabidopsis thaliana. Necrotic lesions were observed in Arabidopsis leaves infiltrated by 1 μM type A trichothecenes such as T-2 toxin. Trichothecene-induced lesions exhibited dead cells, callose deposition, generation of hydrogen peroxide, and accumulation of salicylic acids. Moreover, infiltration by trichothecenes caused rapid and prolonged activation of two mitogen-activated protein kinases and induced expression of both PR-1 and PDF1.2 genes. Thus, type A trichothecenes trigger the cell death by activation of an elicitor-like signaling pathway in Arabidopsis. Although DON did not have such an activity even at 10 μM, translational inhibition by DON was observed at concentrations above 5 μM. These results suggested that DON is capable of inhibiting translation in Arabidopsis cells without induction of the elicitor-like signaling pathway. © 2006 The American Phytopathological Society.., 金沢大学疾患モデル総合研究センター / 金沢大学学際科学実験センター遺伝子研究施設},
 pages = {512--520},
 title = {Fusarium phytotoxin trichothecenes have an elicitor-like activity in Arabidopsis thaliana, but the activity differed significantly among their molecular species},
 volume = {19},
 year = {2006}
}