{"created":"2023-07-27T06:41:43.381480+00:00","id":31003,"links":{},"metadata":{"_buckets":{"deposit":"808c11d8-9cb8-458e-b867-f226b8e4a29e"},"_deposit":{"created_by":3,"id":"31003","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"31003"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00031003","sets":["2229:2230:2231"]},"author_link":["21326","825","52686","52685","20436","24378","52684","658"],"item_4_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2012-05-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"5","bibliographicPageEnd":"379","bibliographicPageStart":"376","bibliographicVolumeNumber":"34","bibliographic_titles":[{"bibliographic_title":"Brain and Development"}]}]},"item_4_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"We report on a 9-year-old boy who presented with acute encephalopathy and hemophagocytic lymphohistiocytosis (HLH). The patient was referred to our hospital because of fever, seizures, and decreased consciousness. He showed moderately elevated levels of proinflammatory cytokines in the cerebrospinal fluid and plasma, and clonal expansion of highly activated CD8 + T cells in the peripheral blood. These CD8 + T cells were found to be larger cells that stained positive for T-cell receptor Vβ13.6, and decreased shortly after steroid therapy. Our findings suggest that his acute encephalopathy was likely a clinical manifestation of HLH, and that immunophenotypic analysis may be helpful for early recognition of HLH in such rare encephalopathy. © 2011 The Japanese Society of Child Neurology.","subitem_description_type":"Abstract"}]},"item_4_publisher_17":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Elsevier / 日本小児神経学会Japanese Society of Child Neurology"}]},"item_4_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"10.1016/j.braindev.2011.07.005","subitem_relation_type_select":"DOI"}}]},"item_4_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://child-neuro-jp.org/","subitem_relation_type_select":"URI"}},{"subitem_relation_type_id":{"subitem_relation_type_id_text":"http://www.elsevier.com/locate/issn/03877604","subitem_relation_type_select":"URI"}}]},"item_4_rights_23":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"© 2011 The Japanese Society of Child Neurology"}]},"item_4_source_id_11":{"attribute_name":"NCID","attribute_value_mlt":[{"subitem_source_identifier":"AA00111153","subitem_source_identifier_type":"NCID"}]},"item_4_source_id_9":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"0387-7604","subitem_source_identifier_type":"ISSN"}]},"item_4_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Wada, Taizo"}],"nameIdentifiers":[{},{},{},{}]},{"creatorNames":[{"creatorName":"Nishimura, Kashiku"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kuroda, Mondo"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"Asai, Erika"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Vu, Quang Van"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Toma, Tomoko"}],"nameIdentifiers":[{},{},{}]},{"creatorNames":[{"creatorName":"Niida, Yo"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"Yachie, Akihiro"}],"nameIdentifiers":[{},{},{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-10-05"}],"displaytype":"detail","filename":"HO-PR-WADA-T-376.pdf","filesize":[{"value":"166.1 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"HO-PR-WADA-T-376.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/31003/files/HO-PR-WADA-T-376.pdf"},"version_id":"bc85c0be-2696-4407-8613-02d4b1f9471f"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"A case of acute encephalopathy with hemophagocytic lymphohistiocytosis and clonal T-cell expansion","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"A case of acute encephalopathy with hemophagocytic lymphohistiocytosis and clonal T-cell expansion"}]},"item_type_id":"4","owner":"3","path":["2231"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-10-05"},"publish_date":"2017-10-05","publish_status":"0","recid":"31003","relation_version_is_last":true,"title":["A case of acute encephalopathy with hemophagocytic lymphohistiocytosis and clonal T-cell expansion"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2023-07-27T20:09:12.781082+00:00"}