@article{oai:kanazawa-u.repo.nii.ac.jp:00031020,
 author = {Kobayashi, Shota and Yokoyama, Shigeru and Maruta, Takahiro and Negami, Masako and Muroyama, Akiko and Mitsumoto, Yasuhide and Iwasa, Kazuo and Yamada, Masahito and Yoshikawa, Hiroaki},
 issue = {1-2},
 journal = {Journal of Neuroimmunology},
 month = {Apr},
 note = {Autoantibody against nicotinic acetylcholine receptor (nAChR) α3 subunit has been implicated in the pathogenesis of paraneoplastic neurological syndrome. To examine the effect of anti-α3 subunit autoantibody on cell-surface nAChRs, we established human embryonic kidney 293 cells stably co-expressing α3 and β4 subunits. Upon incubation with seropositive patient's serum, this cell line showed co-accumulation of patient's IgG and α3 subunits in the cytoplasm. These data support the hypothesis that anti-α3 subunit autoantibody induces internalization of cell-surface nAChRs and thereby impairs synaptic transmission. © 2012 Elsevier B.V. All rights reserved.},
 pages = {102--106},
 title = {Autoantibody-induced internalization of nicotinic acetylcholine receptor α3 subunit exogenously expressed in human embryonic kidney cells},
 volume = {257},
 year = {2013}
}