{"created":"2023-07-27T06:44:19.505852+00:00","id":34510,"links":{},"metadata":{"_buckets":{"deposit":"86edb620-2b62-4205-9097-063ef977b897"},"_deposit":{"created_by":3,"id":"34510","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"34510"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00034510","sets":["2812:2813:2820"]},"author_link":["35","27186"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2014-05-28","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"5p.","bibliographicVolumeNumber":"2012-04-01 – 2014-03-31","bibliographic_titles":[{"bibliographic_title":"平成25(2013)年度 科学研究費補助金 挑戦的萌芽研究 研究成果報告書"},{"bibliographic_title":"2013 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"重油汚染による魚の奇形発生の機構を調べるために、様々なバイオアッセイ系を用いて解析した。その結果、毒物の本体は、水酸化した多環芳香族炭化水素類であり、メダカの胚発生において致死作用があり、ウロコの骨芽細胞及び破骨細胞の活性に影響を与えた。さらに解毒タンパク質の候補になり得る物質を見出すことができた。","subitem_description_type":"Abstract"},{"subitem_description":"Using bioassay systems with fishes, we examined the mechanism of spinal deformity of fish by the heavy oil pollution. As a result, hydroxylated polycyclic aromatic hydrocarbons (OHPAH) provided causing death in early embryogenesis of the medaka, and OHPAH influenced the cell activities in fish scales. We suggested that the main substances of poison causing deformity of the fish are OHPAHs. Furthermore, we found the material which could become a candidate of the detoxification protein.","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:24651044, 研究期間(年度):2012-04-01 – 2014-03-31","subitem_description_type":"Other"},{"subitem_description":"出典：研究課題「重油汚染海水で生まれた魚の脊柱彎曲の機構解明と新規解毒タンパク質によるレスキュー」課題番号24651044\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所）） \n（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-24651044/24651044seika/）を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学医薬保健研究域薬学系","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00034497","subitem_identifier_reg_type":"JaLC"}]},"item_9_publisher_17":{"attribute_name":"公開者","attribute_value_mlt":[{"subitem_publisher":"金沢大学薬学系"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/search/?qm=40115267"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=40115267","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24651044/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-24651044/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-24651044/24651044seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-24651044/24651044seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-10-05"}],"displaytype":"detail","filename":"PH-PR-HAYAKAWA-K-kaken 2014-5p.pdf","filesize":[{"value":"178.2 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"PH-PR-HAYAKAWA-K-kaken 2014-5p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/34510/files/PH-PR-HAYAKAWA-K-kaken 2014-5p.pdf"},"version_id":"5bf86862-7d05-4b71-b8c6-107633ffcf81"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"重油汚染海水で生まれた魚の脊柱彎曲の機構解明と新規解毒タンパク質によるレスキュー","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"重油汚染海水で生まれた魚の脊柱彎曲の機構解明と新規解毒タンパク質によるレスキュー"},{"subitem_title":"Mechanism of the spinal deformity of fish born in heavy oil polluted seawater, and rescue with the new detoxification protein","subitem_title_language":"en"}]},"item_type_id":"9","owner":"3","path":["2820"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-10-05"},"publish_date":"2017-10-05","publish_status":"0","recid":"34510","relation_version_is_last":true,"title":["重油汚染海水で生まれた魚の脊柱彎曲の機構解明と新規解毒タンパク質によるレスキュー"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-07-27T09:25:04.743998+00:00"}