{"created":"2023-07-27T06:44:23.709888+00:00","id":34602,"links":{},"metadata":{"_buckets":{"deposit":"30e89810-8589-4e18-86cc-cb3ae74bec6e"},"_deposit":{"created_by":3,"id":"34602","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"34602"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00034602","sets":["2812:2813:2822"]},"author_link":["24452"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2012-04-13","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"4p.","bibliographicVolumeNumber":"2010-2011","bibliographic_titles":[{"bibliographic_title":"平成23(2011)年度 科学研究費補助金 若手研究(B) 研究成果報告書"},{"bibliographic_title":"2011 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Kita, Daisuke"}],"nameIdentifiers":[{"nameIdentifier":"24452","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"10377385","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=10377385"},{"nameIdentifier":"10377385","nameIdentifierScheme":"研究者番号","nameIdentifierURI":"https://nrid.nii.ac.jp/nrid/1000010377385"}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"毛様星細胞腫における病理組織と遺伝子変異による診断の相関、ならびに客観性の有無を検討した。その結果、遺伝子異常の有無が、病理診断と比較し概ね妥当であることを確認した。この中で、BRAF遺伝子変化の見られなかった腫瘍について、毛様星細胞腫ではなく退形成星細胞腫と診断すべき症例を詳細に検討し、FAS遺伝子異常とP53遺伝子異常が重複したことで悪性化を来たしたことが示された。","subitem_description_type":"Abstract"},{"subitem_description":"We assessed the relationship between histology and genetic alteration of pilocytic astrocytomas, and found there were strong correlation between BRAF gene alteration and histological accuracy. We then researched a tumor which had been diagnosed as pilocytic astrocytoma. We re-diagnosed it as anaplastic astrocytoma and found that the tumor could be associated with concomitant mutations of FAS and TP53, and it might progress secondarily from the long-standing diffuse astrocytoma via uncommon genetic alterations.","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"出典：研究課題「小児期星細胞腫の特徴および悪性化に関わる遺伝子異常に関する研究」課題番号22791337\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所）） \n（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-22791337/22791337seika/）を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学附属病院","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00034589","subitem_identifier_reg_type":"JaLC"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=10377385","subitem_relation_type_select":"URI"}},{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-22791337/","subitem_relation_type_select":"URI"}},{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-22791337/22791337seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"喜多, 大輔"}],"nameIdentifiers":[{"nameIdentifier":"24452","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"10377385","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://kaken.nii.ac.jp/ja/search/?qm=10377385"},{"nameIdentifier":"10377385","nameIdentifierScheme":"研究者番号","nameIdentifierURI":"https://nrid.nii.ac.jp/nrid/1000010377385"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-10-05"}],"displaytype":"detail","filename":"HO-PR-KITA-D-kaken 2012-4p.pdf","filesize":[{"value":"225.3 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"HO-PR-KITA-D-kaken 2012-4p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/34602/files/HO-PR-KITA-D-kaken 2012-4p.pdf"},"version_id":"30b0dc6b-f2d5-4d2c-bf39-462974aa48fd"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"小児期星細胞腫の特徴および悪性化に関わる遺伝子異常に関する研究","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"小児期星細胞腫の特徴および悪性化に関わる遺伝子異常に関する研究"},{"subitem_title":"Genetic alteration of pediatric astrocytic tumors associated with malignant transformation","subitem_title_language":"en"}]},"item_type_id":"9","owner":"3","path":["2822"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-10-05"},"publish_date":"2017-10-05","publish_status":"0","recid":"34602","relation_version_is_last":true,"title":["小児期星細胞腫の特徴および悪性化に関わる遺伝子異常に関する研究"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2024-07-01T05:59:00.856075+00:00"}