{"created":"2023-07-27T06:44:25.987561+00:00","id":34654,"links":{},"metadata":{"_buckets":{"deposit":"71a5324f-d266-4890-89d7-c6f3b9175fa2"},"_deposit":{"created_by":3,"id":"34654","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"34654"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00034654","sets":["2812:2813:2823"]},"author_link":["80517","2640"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2011-05-11","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"5p.","bibliographicVolumeNumber":"2008-2010","bibliographic_titles":[{"bibliographic_title":"平成22(2010)年度 科学研究費補助金 基盤研究(C) 研究成果報告書"},{"bibliographic_title":"2010 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"It is believed that strain-induced fluid flow (SIFF) stimulates osteogenic response of bone cells, resulting in adaptive bone formation. However, the mechanism of the osteogenic ability of SIFF is not fully understood. In this research, the ability of SIFF was investigated using regenerative bones made of osteoblasts and porous scaffolds. The results showed that SIFF promotes the ostegenesis of regenerated bones. This ability of SIFF was influenced by the porosity and material of scaffold, and the frequency of mechanical stimulation. These findings contribute to further understanding of the bone mechano-biology and the progress of bone tissue engineering. ","subitem_description_type":"Abstract"},{"subitem_description":"骨基質内で生じるひずみ誘導型液体流動(SIFF)は骨細胞を刺激し骨形成反応を促すと考えられている。しかし、SIFFによる骨形成反応促進機構は十分に理解されていない。そこで本研究では、骨芽細胞と多孔質担体から成る培養再生骨を用いて、SIFFの骨形成反応促進効果を調べた。その結果、SIFFの骨形成反応促進効果は担体の多孔性、素材、細胞密度および刺激周波数の影響を受けることが分かった。本成果は、骨生体力学のより一層の理解と骨の再生医療発展へ貢献するものである。","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:20560070, 研究期間(年度):2008–2010","subitem_description_type":"Other"},{"subitem_description":"出典：研究課題「ひずみ誘導型液体流動による骨形成反応促進効果の実験的検証」課題番号20560070\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所）） \n（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-20560070/20560070seika/）を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学環日本海域環境研究センター","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00034641","subitem_identifier_reg_type":"JaLC"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=20262602","subitem_relation_type_select":"URI"}},{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20560070/","subitem_relation_type_select":"URI"}},{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-20560070/20560070seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-10-05"}],"displaytype":"detail","filename":"SC-PR-TANAKA-S-kaken 2011-5p.pdf","filesize":[{"value":"529.3 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"SC-PR-TANAKA-S-kaken 2011-5p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/34654/files/SC-PR-TANAKA-S-kaken 2011-5p.pdf"},"version_id":"09b3ae7a-063c-48a5-b88a-4263f91a5de5"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"ひずみ誘導型液体流動による骨形成反応促進効果の実験的検証","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"ひずみ誘導型液体流動による骨形成反応促進効果の実験的検証"},{"subitem_title":"Experimental validation of osteogenic effect of strain-induced fluid flow","subitem_title_language":"en"}]},"item_type_id":"9","owner":"3","path":["2823"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-10-05"},"publish_date":"2017-10-05","publish_status":"0","recid":"34654","relation_version_is_last":true,"title":["ひずみ誘導型液体流動による骨形成反応促進効果の実験的検証"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-07-27T13:18:46.882158+00:00"}