{"created":"2023-07-27T06:44:26.652050+00:00","id":34669,"links":{},"metadata":{"_buckets":{"deposit":"97250b26-bf58-4d34-8e56-e153bd4ebdad"},"_deposit":{"created_by":3,"id":"34669","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"34669"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00034669","sets":["2812:2813:2824"]},"author_link":["74756","273"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2010-04-04","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"4p.","bibliographicVolumeNumber":"2007-2009","bibliographic_titles":[{"bibliographic_title":"平成21(2009)年度 科学研究費補助金 基盤研究(C) 研究成果報告書"},{"bibliographic_title":"2009 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"548の心筋症家系(肥大型心筋症400家系、拡張型心筋症148家系)に関して、発端者ならびにその家族の臨床所見および遺伝子変異を解析した。肥大型心筋症の遺伝子変異保因者臨床像について特に左室収縮機能に着目した所、ミオシン群75例(心筋ベータミオシン重鎖遺伝子およびミオシン結合蛋白C遺伝子)とトロポニン群75例(心筋トロポニンT遺伝子および心筋トロポニンI遺伝子)では、収縮不全(左室駆出率50%未満)の合併に違いが認められた。40歳以上の症例における収縮不全発症率について、トロポニン群ではミオシン群と比較して有意に発症率が高いことが示された。","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:19590807, 研究期間(年度):2007–2009","subitem_description_type":"Other"},{"subitem_description":"出典：研究課題「肥大型及び拡張型心筋症の病態解明: 分子遺伝学的、臨床機能解析的、両アプローチから」課題番号19590807\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所）） \n（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-19590807/19590807seika/）を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学医薬保健研究域保健学系","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00034656","subitem_identifier_reg_type":"JaLC"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=40361993","subitem_relation_type_select":"URI"}},{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19590807/","subitem_relation_type_select":"URI"}},{"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-19590807/19590807seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-10-05"}],"displaytype":"detail","filename":"ME-PR-FUJINO-N-kaken 2010-4p.pdf","filesize":[{"value":"293.5 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"ME-PR-FUJINO-N-kaken 2010-4p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/34669/files/ME-PR-FUJINO-N-kaken 2010-4p.pdf"},"version_id":"a6da4e1b-17b3-4f71-8059-e94f5de90387"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"肥大型及び拡張型心筋症の病態解明: 分子遺伝学的、臨床機能解析的、両アプローチから","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"肥大型及び拡張型心筋症の病態解明: 分子遺伝学的、臨床機能解析的、両アプローチから"},{"subitem_title":"Research of the hypertrophic and dilated cardiomyopathy: From both approaches of the molecular genetics and the clinical functional analysis","subitem_title_language":"en"}]},"item_type_id":"9","owner":"3","path":["2824"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-10-05"},"publish_date":"2017-10-05","publish_status":"0","recid":"34669","relation_version_is_last":true,"title":["肥大型及び拡張型心筋症の病態解明: 分子遺伝学的、臨床機能解析的、両アプローチから"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-07-27T13:16:21.667303+00:00"}