{"created":"2023-07-27T06:50:20.395914+00:00","id":43081,"links":{},"metadata":{"_buckets":{"deposit":"f3a0cdd3-a4e0-48dd-a87d-ad726896c13b"},"_deposit":{"created_by":18,"id":"43081","owners":[18],"pid":{"revision_id":0,"type":"depid","value":"43081"},"status":"published"},"_oai":{"id":"oai:kanazawa-u.repo.nii.ac.jp:00043081","sets":["2812:2813:2823"]},"author_link":["69296","22954"],"item_9_biblio_info_8":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2011-05-18","bibliographicIssueDateType":"Issued"},"bibliographicPageStart":"6p.","bibliographicVolumeNumber":"2006-2010","bibliographic_titles":[{"bibliographic_title":"平成22(2010)年度 科学研究費補助金 基盤研究(S) 研究成果報告書"},{"bibliographic_title":"2010 Fiscal Year Final Research Report","bibliographic_titleLang":"en"}]}]},"item_9_creator_33":{"attribute_name":"著者別表示","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{}],"nameIdentifiers":[{},{}]}]},"item_9_description_21":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"肝臓は、糖・タンパク・脂質の代謝や薬物および異物の解毒を専門とする巨大な臓器である。大量の物質を血液から取り込んで代謝し、全身の臓器に代謝物を供給する。21世紀の最大の課題である動脈硬化、糖尿病、癌、炎症といった栄養状態が関与する症候群に、肝臓の機能破綻が大きく関与している可能性を示した。本研究は、過栄養状態における肝臓の変化を明らかにすることによって新たな肝臓病の疾病概念を確立するとともに、肝臓機能の破綻によって生じる肝代謝異常の診断および治療法開発の基盤となるべき研究を行った。","subitem_description_type":"Abstract"},{"subitem_description":"Liver uptakes varieties of nutrients, metabolizes glucose, proteins, lipids, and drugs and systemically delivers the metabolites through blood streams. We have demonstrated that nutrition related diseases such as atherosclerosis, diabetes, cancer, and inflammation are partially caused by the dysfunction of liver which uptakes excess nutrients. We established the concept of the liver related diseases, and showed the fundamental findings for the development of the diagnosis and therapy for the diseased liver.","subitem_description_type":"Abstract"}]},"item_9_description_22":{"attribute_name":"内容記述","attribute_value_mlt":[{"subitem_description":"研究課題/領域番号:18109008, 研究期間(年度):2006-2010","subitem_description_type":"Other"},{"subitem_description":"出典：研究課題「過栄養状態における肝臓機能の破綻と生活習慣病の研究」課題番号18109008\n（KAKEN：科学研究費助成事業データベース（国立情報学研究所）） \n（https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-18109008/18109008seika/）を加工して作成","subitem_description_type":"Other"}]},"item_9_description_5":{"attribute_name":"提供者所属","attribute_value_mlt":[{"subitem_description":"金沢大学医薬保健研究域医学系","subitem_description_type":"Other"}]},"item_9_identifier_registration":{"attribute_name":"ID登録","attribute_value_mlt":[{"subitem_identifier_reg_text":"10.24517/00049428","subitem_identifier_reg_type":"JaLC"}]},"item_9_relation_28":{"attribute_name":"関連URI","attribute_value_mlt":[{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/search/?qm=60185923"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/search/?qm=60185923","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18109008/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18109008/","subitem_relation_type_select":"URI"}},{"subitem_relation_name":[{"subitem_relation_name_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-18109008/18109008seika/"}],"subitem_relation_type_id":{"subitem_relation_type_id_text":"https://kaken.nii.ac.jp/report/KAKENHI-PROJECT-18109008/18109008seika/","subitem_relation_type_select":"URI"}}]},"item_9_version_type_25":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-12-22"}],"displaytype":"detail","filename":"ME-PR-KANEKO-S-kaken 2011-6p.pdf","filesize":[{"value":"227.1 kB"}],"format":"application/pdf","licensetype":"license_11","mimetype":"application/pdf","url":{"label":"ME-PR-KANEKO-S-kaken 2011-6p.pdf","url":"https://kanazawa-u.repo.nii.ac.jp/record/43081/files/ME-PR-KANEKO-S-kaken 2011-6p.pdf"},"version_id":"a1d3a201-3a23-4a0b-a0b3-7ea952ac0a33"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"research report","resourceuri":"http://purl.org/coar/resource_type/c_18ws"}]},"item_title":"過栄養状態における肝臓機能の破綻と生活習慣病の研究","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"過栄養状態における肝臓機能の破綻と生活習慣病の研究"},{"subitem_title":"Disturbance of hepatic function and overnutrition-related diseases","subitem_title_language":"en"}]},"item_type_id":"9","owner":"18","path":["2823"],"pubdate":{"attribute_name":"公開日","attribute_value":"2017-12-22"},"publish_date":"2017-12-22","publish_status":"0","recid":"43081","relation_version_is_last":true,"title":["過栄養状態における肝臓機能の破綻と生活習慣病の研究"],"weko_creator_id":"18","weko_shared_id":-1},"updated":"2023-07-27T13:18:24.250008+00:00"}